Research Training in Gastroenterology

参见说明）： 这是一个竞争性的延续申请，用于更新胃肠病学培训计划， 1999年首次资助。自那时以来，已有20名受训人员得到支助，其中除4人外，其余均为全职人员 学术职位，或全职研究行业，或仍在培训。该计划的目标是提供 为致力于调查研究事业的年轻研究人员提供两三年的研究培训 胃肠病学或相关领域。研究培训的类型包括基础、转化或临床 研究，或两者的结合。受训者可能是医学博士、医学博士-博士或完成临床或 研究生培训，并正在寻求进一步的研究培训在胃肠病学。培训将主要包括 指导研究，这将提供强烈的实践经验。广泛的教学课程菜单， 还将举办讲习班、研讨会和会议。以病人为导向的研究的受训者将 完成课程和论文要求，以获得MMS，MPH或同等学位。所有 受训人员将提交K系列NIH奖的资助申请或研究支持 在研究培训的第三年的基础。 学员将由具有广泛兴趣和专业知识的经验丰富的研究导师指导 从基础细胞和分子生物学到临床研究。由凯利博士组成的培训委员会， 罗布森，特霍斯特和哀叹和一个或两个其他培训教师将监测整个研究培训 程序，选择合适的候选人，并监测进展。培训生研究计划将在 与该部门的卓越临床中心相结合的四大领域：1.）肠道感染 （2）豁免权。肝损伤和纤维化3.）血管生物学和4.）上皮生物学。培训 该计划将利用地理信息部门、各部门内优秀的地理信息研究基地 哈佛大学医学院和公共卫生学院。培训计划将 还受益于BIDMC组织良好、资金充足的综合临床研究中心， 以及两个消化系统疾病中心，一个在哈佛医学院和一个 第二个在马萨诸塞州总医院政府情报司在征聘女性工作人员方面有着良好的记录， 该中心还为少数群体学员和教员提供培训，并为今后的少数群体外联和招聘制定了积极的计划。 相关性（参见说明）： 该计划将解决一般医学和特别是胃肠病学的一个关键问题： 专注于GI和肝脏疾病的训练有素的医生-科学家和基础研究人员的供应减少。 该计划将整合实验室研究与临床问题和问题，以更好地解决 在我们专业的诊断和治疗方面存在信息缺口。我们的最终目标是培养出 能够成功地竞争启动研究资金和入门级教师职位， 继续表现出对基础或临床研究的实质性承诺。

See instructions): This is a competing continuation application for renewal of a training program in gastroenterology that was first funded in 1999. Since then, 20 trainees have been supported, of whom all but four are in full time academic positions, or full-time research in industry, or still in training. The goal of this program is to provide two or three years of research training for young researchers committed to a career in investigative gastroenterology or allied fields. The types of research training include basic, translational or clinical research, or combinations of these. Trainees may be MDs, MD-PhDs or PhDs who have finished clinical or graduate training and are seeking further research training in gastroenterology. Training will consist primarily of mentored research that will provide intense hands-on experience. An extensive menu of didactic courses, workshops, seminars and conferences will also be provided. Trainees in patient-oriented research will be expected to complete course work and thesis requirements to obtain an MMS, MPH or equivalent degree. All trainees will be expected to submit grant applications for K-series NIH awards or support from research foundations during the 3rd year of research training. Trainees will be supervised by experienced research mentors with a wide range of interests and expertise from basic cellular and molecular biology to clinical research. A training committee composed of Drs. Kelly, Robson, Terhorst and Lament and one or two other training faculty will monitor the overall research training program, select suitable candidates and monitor progress. Trainee research programs will be available in four broad areas that are integrated with clinical centers of excellence in the Division: 1.) Intestinal Infection and Immunity 2.) Liver Injury and Fibrosis 3.) Vascular Biology and 4.) Epithelial Biology. The training program will take advantage of the outstanding Gl research base within the Gl Division, the Departments of Medicine and Surgery and at harvard Medical School and School of Public Health. The training program will also benefit from the availability of a well organized and funded General Clinical Research Center at BIDMC, as well as the close proximity of two Digestive Disease Centers, one at Harvard Medical School and a second at Massachusetts General Hospital. The Gl Division has a good track record of recruitment of female and minority trainees and faculty, and has an active plan for future minority outreach and recruitment. RELEVANCE (See instructions): This program will address a critical issue in medicine in general and gastroenterology in particular: the dwindling supply of well-trained physician-scientists and basic researchers focused on Gl and liver diseases. The program will integrate bench research with clinical questions and problems to better address the information gaps in diagnosis and treatment in our specialty. Our ultimate goal is to produce individuals who are able to compete successfully for start-up research funding and for entry level faculty positions and who continue to exhibit a substantial commitment to basic or clinical research.