Scripps Translational Science Institute
Scripps Translational Science Institute
批准号:
9062542
负责人:
Eric Jeffrey Topol
金额:
$78.21万
依托单位国家:
美国
项目类别:
财政年份:
2013
资助国家:
美国
项目状态:
已结题
起止时间:
2013-09-26 至 2018-04-30
关键词:
Adverse effectsAreaBiologicalBiosensorClinical ResearchCommunitiesCountryDataDiagnosisDiseaseFoundationsFutureGenomicsHealthHealthcareHealthcare SystemsHumanIndividualInstitutesInstitutionInstructionMass ScreeningMedicalMedicinePatientsPharmaceutical PreparationsPhysiologicalPublic HealthResearchResearch InfrastructureResearch InstituteResourcesScientistServicesTraining SupportTranslational ResearchUnited StatesWireless Technologycareer developmentcosteffective therapyimprovedindividualized medicineinformatics infrastructureinnovationprogramssupercomputertoolwhole genome
中文摘要
斯克里普斯翻译科学研究所(STSI)旨在支持和促进有影响力的翻译和
临床研究不仅为斯克里普斯机构,包括斯克里普斯研究所和
斯克里普斯健康,但也是一个广泛的合作调查网络,从拉乔里亚梅萨
斯克里普斯计划结合了美国最大的独立生物医学研究所,
这个国家在圣地亚哥拥有占主导地位的医疗保健系统,沿着与
圣地亚哥超级计算机中心是4个国家资源中心之一。我们的创新领域
基础设施是信息学、基因组学和无线医学。每个领域都有一个显著的变革性
未来医学的潜力和改善公众的健康。基因组学的重大进展,
无线技术创造了以前无法想象的数据洪流,但随着先进的
分析能力有一个显着的机会,使用这些数据来个性化医疗,定义
每一个独特的人类在多个层面-生物,生理和解剖。
通过个体化用药,有一个科学的基础,更有效的治疗,避免重大
副作用,一种更精确的医疗保健手段,以及降低成本。每个人的数据
信息可以通过无线生物传感器或整个基因测序等新工具来捕获。
基因组STSI在这些工具方面具有特殊的专业知识,其中不仅包括收集数据,
上级分析能力。这建立了一个创新的基础设施,
资源和服务的高生产力的研究网络-一个已经拆除了筒仓,
基础科学家和临床医生。此外,这些资源支持培训和
未来医学领导者的职业发展。
相关性(参见说明):
今天的医学实践包括大规模筛查和对所有患者使用相同的药物
一个特定的诊断。我们新发现的定义每个人的医学本质的能力,
未来更有效、更安全、更便宜的医疗保健方式。通过将一个
STSI是一个非常有才华和富有成效的研究团体,它将推动这种新的医学形式。
英文摘要
The Scripps Translational Science Institute (STSI) aims to support and catalyze impactful translational and
clinical research for not only the Scripps institutions, consisting of The Scripps Research Institute and
Scripps Health, but also an extensive collaborating investigative network that extends from the La Jolia Mesa
throughout the United States.The Scripps program combines the largest independent biomedical institute in
the country with the dominant health care system in San Diego, along with an extensive partnership with the
San Diego Supercomputer Center, one of the 4 national resource centers of its kind. Our areas of innovative
infrastructure are informatics, genomics, and wireless medicine. Each area has a remarkably transformative
potential for the future of medicine and improving the health of the public. Major advances in genomics and
wireless technologies have created data torrents that were previously unimaginable, but with advanced
analytical capabilities there is a remarkable opportunity to use such data to individualize medicine, defining
each unique human being at multiple levels - biological, physiological, and anatomical.
By individualizing medicine, there is a scientific foundation for more effective treatments, avoidance of major
side effects, a far more precise means of rendering health care, and lowering of costs. Each individual's data
and information can be captured with such new tools as wireless biosensors or sequencing of the entire
genome. STSI has particular expertise in these tools, which includes not only gathering the data but also
superior analytical capabilites. This sets up an innovative infrastructure to provide disease-agnostic
resources and services for a highly productive research network - one that has dismantled the silos that
previously existed of basic scientists and clinicians. Furthermore, these resources support the training and
career development of the leaders of medicine for the future.
RELEVANCE (See instructions):
Medicine as practiced today consists of mass screening and the use of the same medications for all patients
with a particular diagnosis. Our newfound ability to define the medical essence of each individual paves the
way for a more efficient, safer, and less expensive form of healthcare in the future. By bringing together an
exceptionally talented and productive research community, STSI will catapult this new form of medicine.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Scripps Clinical and Translational Science Hub
-
批准号:10621679
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项目类别:
-
资助金额:$602.98万
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财政年份:2023
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负责人:Eric Jeffrey Topol
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依托单位:
The Participant Center: Empowering All of Us Research Program participation across the United States
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批准号:10774158
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项目类别:
-
资助金额:$5400.0万
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财政年份:2023
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负责人:Eric Jeffrey Topol
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依托单位:
Technology to Empower Changes in Health (TECH) Network Participant Technologies Center
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批准号:10013434
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项目类别:
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资助金额:$944.61万
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财政年份:2019
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负责人:Eric Jeffrey Topol
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依托单位:
Scripps Translational Science Institute
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批准号:10173181
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项目类别:
-
资助金额:$9.78万
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财政年份:2018
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负责人:Eric Jeffrey Topol
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依托单位:
Scripps Translational Science Institute
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批准号:10159148
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项目类别:
-
资助金额:$18.27万
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财政年份:2018
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负责人:Eric Jeffrey Topol
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依托单位:
Scripps Translational Science Institute
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批准号:10159338
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项目类别:
-
资助金额:$575.94万
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财政年份:2018
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负责人:Eric Jeffrey Topol
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依托单位:
Scripps Translational Science Institute
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批准号:10401476
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项目类别:
-
资助金额:$575.94万
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财政年份:2018
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负责人:Eric Jeffrey Topol
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依托单位:
Scripps Translational Science Institute
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批准号:10660851
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项目类别:
-
资助金额:$13.22万
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财政年份:2018
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负责人:Eric Jeffrey Topol
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依托单位:
Technology to Empower Changes in Health (TECH) Network Participant Technologies Center
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批准号:10368012
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项目类别:
-
资助金额:$2237.89万
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财政年份:2016
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负责人:Eric Jeffrey Topol
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依托单位:
Technology to Empower Changes in Health (TECH) Network Participant Technologies Center
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批准号:10011913
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项目类别:
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资助金额:$3341.99万
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财政年份:2016
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负责人:Eric Jeffrey Topol
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依托单位:
Technology to Empower Changes in Health (TECH) Network Participant Technologies Center
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批准号:10684957
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项目类别:
-
资助金额:$1560.18万
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财政年份:2016
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负责人:Eric Jeffrey Topol
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依托单位:
Scripps Translational Science Institute
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批准号:8743357
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项目类别:
-
资助金额:$537.87万
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财政年份:2013
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负责人:Eric Jeffrey Topol
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依托单位:
Scripps Translational Science Institute
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批准号:8916876
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项目类别:
-
资助金额:$11.27万
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财政年份:2013
-
负责人:Eric Jeffrey Topol
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依托单位:
Scripps Translational Science Institute
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批准号:9062543
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项目类别:
-
资助金额:$20.32万
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财政年份:2013
-
负责人:Eric Jeffrey Topol
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依托单位:
Scripps Translational Science Institute
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批准号:9062544
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项目类别:
-
资助金额:$530.93万
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财政年份:2013
-
负责人:Eric Jeffrey Topol
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依托单位:
Scripps Translational Science Institute
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批准号:8743355
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项目类别:
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资助金额:$71.57万
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财政年份:2013
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负责人:Eric Jeffrey Topol
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依托单位:
Scripps Translational Science Institute
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批准号:9265537
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项目类别:
-
资助金额:$31.68万
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财政年份:2013
-
负责人:Eric Jeffrey Topol
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依托单位:
Scripps Translational Science Institute
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批准号:9265535
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项目类别:
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资助金额:$492.85万
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财政年份:2013
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负责人:Eric Jeffrey Topol
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依托单位:
Scripps Translational Science Institute
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批准号:8721045
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项目类别:
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资助金额:$19.45万
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财政年份:2013
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负责人:Eric Jeffrey Topol
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依托单位:
Scripps Translational Science Institute
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批准号:8721054
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项目类别:
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资助金额:$297.01万
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财政年份:2013
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负责人:Eric Jeffrey Topol
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依托单位:
国内基金
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批准号:2021JJ40433
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项目类别:省市级项目
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资助金额:--
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批准年份:2021
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负责人:孙磊
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依托单位:
寄主诱导梢腐病菌AreA和CYP51基因沉默增强甘蔗抗病性机制解析
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批准号:32001603
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资助金额:24.0万元
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批准年份:2020
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负责人:段真珍
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依托单位:
AREA国际经济模型的移植.改进和应用
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批准号:18870435
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项目类别:面上项目
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资助金额:2.0万元
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批准年份:1988
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负责人:史树中
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依托单位: