Institutional Training Grant in Pediatric Gastroenterology

项目摘要/摘要 本申请是第三次更新儿科机构培训计划(T32) 科罗拉多大学医学院(CUSOM)的胃肠病、肝病和营养学 科罗拉多州奥罗拉市安舒茨医学院的科罗拉多州儿童医院。我们的总体目标是 T32研究培训计划是为不同的博士后实习生群体提供 特殊的监督培训和指导经验，使他们能够发展或提高他们的 研究技能、知识和恩赐精神为成功的儿科做准备 胃肠病学/肝病学/营养学相关研究生涯。这项计划的基本原理 是利用安舒茨医学院提供的强大的物理和科学协同效应， 优秀、敬业和经验丰富的研究人员，以及一大批潜在的申请者。二 提供研究培训的途径，以培养基础实验室科学家或临床/翻译/ 健康结果科学家，利用CUSOM在基础、翻译、临床和健康方面的资源 以结果为基础的研究。研究培训将侧重于四个一般科学主题： 组织损伤和修复，先天免疫和微生物组研究，临床和健康结果研究， 干细胞生物学和再生医学。T32教职员工包括32名科学家，他们的资产约为4700万美元 美元的赠款资金和非常成功的培训记录。基础研究经验通过以下方式得到增强 研究生课程、研讨会和多学科会议。临床实习生--翻译或健康 结果研究将参加CUSOM临床科学硕士研究生项目 并将利用科罗拉多州临床和转化科学研究所的基础设施。这项研究 培训被设计为2-3年的计划，从副专业奖学金的第二年开始。合资格 候选人主要来自国家认可的儿科胃肠病学会， 其他学科包括新生儿学、营养学和相关基础科学领域的候选人的潜力。 为研究员提供至少80%的受保护时间，以便在有指导和有组织的 环境。教育和研究体验的质量将由 实习生、导师和执行委员会，有定义的指标和持续的改进过程。中的 到2019年将完成T32培训的28名学员，75%将拥有全职学术职位和 正在发展他们的研究事业。要求续设5个培训职位。

Project Summary/ Abstract This application is for the third renewal of the Institutional Training Program (T32) in Pediatric Gastroenterology, Hepatology and Nutrition at the University of Colorado School of Medicine (CUSOM) and Children’s Hospital Colorado at the Anschutz’s Medical Campus in Aurora, Colorado. The overall goal of our T32 research training program is to provide a diverse group of post-doctoral trainees with an exceptional supervised training and mentoring experience, to allow them to develop or enhance their research skills, knowledge and grantsmanship in preparation for a successful pediatric gastroenterology/ hepatology/nutrition- related research career. The underlying rationale for this program is to take advantage of the strong physical and scientific synergies provided at the Anschutz Medical Campus, an outstanding committed and experienced research faculty, and a large pool of potential applicants. Two pathways of research training are offered to produce Basic Laboratory Scientists or Clinical/ Translational/ Health Outcomes Scientists, leveraging the resources at CUSOM in basic, translational, clinical and health outcomes-based research. Research training will be focused in four general scientific themes: Mechanisms of Tissue Injury and Repair, Innate Immunity and Microbiome Research, Clinical and Health Outcomes Research, and Stem Cell Biology and Regenerative Medicine. The T32 faculty includes 32 scientists with ~$47 million dollars in grant funding and a highly successful training record. Basic research experiences are augmented by graduate courses, seminars and multidisciplinary meetings. Trainees in clinical-translational or health outcomes research will participate in the Master of Science in Clinical Sciences Graduate Program of CUSOM and will leverage the infrastructure of the Colorado Clinical and Translational Sciences Institute. The research training is designed to be a 2-3 year program, beginning in the 2nd year of subspecialty fellowship. Eligible candidates are primarily drawn from the nationally recognized fellowship in Pediatric Gastroenterology, with the potential for candidates in other disciplines including neonatology, nutrition and related basic science fields. Fellows are provided a minimum of 80% protected time for research training in a mentored and structured environment. The quality of the educational and research experiences will be closely monitored by the trainees, mentors and Executive Committee, with defined metrics and ongoing improvement processes. Of the 28 trainees who will have completed the T32 training by 2019, 75% will have full-time academic positions and are developing their research careers. The continuation of 5 training positions is requested.