The Clinical Translational Research Certificate of Added Qualification Program

项目概要/摘要。 我们正在请求支持一个新的跨学科的"临床转化研究证书， 资格"（CTR-CAQ）培训计划的研究生就读于任何博士学位授予研究生 贝勒医学院（Baylor College of Medicine）该计划得到了联合国领导层的大力支持， 研究生教师和学生。严格的两年制课程的使命是为寻求 职业生涯专注于将生物医学发现转化为分子医学进展， 领导有效的翻译研究所需的基础知识和专业技能的教育 团队该计划的基本原理建立在我们14年成功整合 在转化生物学和分子医学的单一研究生课程中进行转化研究培训 （TBMM）。TBMM毕业生的多元化群体目前正在从事多种多样的翻译研究 careers.这一成功为所有研究生都能获得翻译研究培训提供了前提 在生物医学科学的所有分支学科发展多样化的研究队伍至关重要。 这种需要不能仅仅依赖于医生科学家，必须包括博士科学家的多样化干部。 内部评估TBMM成果，审查国家教育和技能发展优先事项， 提高越来越重要的翻译研究队伍的职业准备，形成基础， 新计划的可衡量目标。我们将联合收割机的最佳组成部分的传统TBMM （a）征聘和保留一批多样化的干部， （B）导师培训、导师协作和导师监督;（c） 实践技能发展和转化研究的职业准备，包括监管培训 知识及其在有意义的以团队为基础的科学和领导方面的实际应用;（d）正式 评估总体方案的有效性，受训人员在培训过程中个人的感知效益 通过该方案，并在该方案完成后的短期和长期成果。 因此，该计划的主要目标是：（1）通过以下方式为学生从事翻译研究做好准备 结合形成性教学，技能发展研讨会和临床经验学习 研究设置与指导翻译研究项目交付的形式，一个顶点项目 与团队合作的组成部分;（2）有效地整合这一计划与培训的主要博士- 培训计划;（3）开发和监控最佳指导实践;（4）正式评估计划 以及学生参加CTR-CAQ计划期间和之后的个人成果。我们预计， 该计划将培养一批转化分子医学和团队研究的领导者，他们将 继续从事各种学术和非学术生物医学科学事业。

Project Summary/Abstract. We are requesting support for a new interdisciplinary “Clinical Translational Research Certificate of Added Qualification” (CTR-CAQ) training program for graduate students enrolled in any of the PhD-awarding graduate programs at Baylor College of Medicine (BCM). This program has strong support from BCM leadership, graduate faculty and students. The mission of the rigorous two-year program is to provide students who seek a career focused on the translation of biomedical discoveries into molecular medicine advances, with integrated education in the foundational knowledge and professional skills required to lead effective translational research teams. The rationale for this program builds upon our 14-year experience of successfully integrating translational research training in a single graduate program in Translational Biology and Molecular Medicine (TBMM). A diverse group of TBMM graduates are currently engaged in multiple diverse translational research careers. This success provided the premise that translational research training accessible to all graduate students at BCM is vital to develop a diverse research workforce in all subdisciplines of biomedical science. This need cannot be reliant on physician-scientists alone and must include a diverse cadre of PhD scientists. Internal evaluation of TBMM outcomes and review of national priorities for education and skills development to enhance career preparedness of an increasingly important translational research workforce, form the basis of measurable objectives of the new program. We will combine the best components of the legacy TBMM program with several new innovative strategies for: (a) Recruitment and retention of a diverse cadre of students in the translational workforce; (b) Mentor training, mentor collaboration, and mentorship oversight; (c) Practical skill development and career preparedness for translational research, including training in regulatory knowledge and its practical application in meaningful team-based science, and in leadership; (d) Formal evaluation of overall programmatic effectiveness, individual perceived benefits during the trainee trajectory through the program, and of short- and long-term outcomes upon completion of the program. Thus, the primary objectives of the program are: (1) to prepare students for careers in translational research by combining formative didactic teaching, skill development workshops and experiential learning in clinical research settings with a mentored translational research project deliverable in the form of a capstone project with team-work components; (2) to effectively integrate this program with the training in the primary PhD- training programs; (3) to develop and monitor best mentorship practices; (4) to formally evaluate programmatic and individual outcomes during and after students participate in the CTR-CAQ program. We anticipate that this program will develop a cadre of leaders in translational molecular medicine and team-based research who will remain engaged in a diverse array of academic and non-academic biomedical science careers.