Nanoparticulate Coatings Enhance Ion Detection
Nanoparticulate Coatings Enhance Ion Detection
批准号:
10259237
负责人:
John Albert Schultz
金额:
$79.95万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2014
资助国家:
美国
项目状态:
已结题
起止时间:
2014-09-25 至 2023-08-31
关键词:
AlloysAreaAtmosphereBiological SciencesChargeComputer softwareDataDepositionDetectionDoseElectronsEquipmentFilmFluorescence MicroscopyGasesGoalsHeightHeliumIndividualIonsKineticsLegal patentMasksMeasurementMeasuresMethodsMicroscopeMicroscopyModelingModificationMorphologyOutcomePerformancePhasePhotonsPhysicsPhysiologic pulsePositron-Emission TomographySalesSourceSurfaceTechniquesTechnologyTestingThickThinnessTransmission Electron MicroscopyUnited States National Institutes of HealthWorkatomic layer depositionbasedata acquisitiondetectorimprovedion mobilitymass spectrometermicroporenanoparticulatenanoscaleparticlesuccesstime of flight mass spectrometrytool
中文摘要
项目摘要
一种新的提高现有薄膜增益和灵敏度的薄膜沉积技术
微通道离子探测器在先前完成的NIH第一阶段中得到证实
这些薄膜的二次电子(SE)产额随着氦离子剂量的增加而提高
高达>;100库仑/厘米2,而未镀膜探测器的电子产额为第一表面
在1库仑/cm~2后下降。美国国立卫生研究院第二阶段将使用这些薄膜来改变元素
第一表面的成分和形貌,以增加第一次命中SE的产量并延长
沉积层的寿命。探测器测试将在内部进行离子和电子测试
消息来源。
将这些薄膜涂层涂覆到MCP侧壁上的方法(除了
覆盖前探测器表面)应增加探测器增益并实质上延长
商用MCP的探测器寿命。
我们将强调在罗格斯大学使用蔡司猎户座氦离子显微镜进行
MCP脉冲高度、增益和第一表面二次电子的加速寿命测试
从单个毛孔中产生。核爆首发区域元素组成变化
微通道孔也将由纳米级卢瑟福背散射来确定
猎户座和将与寿命和产量测量相关。这两种技术的结合
配置了Ionwerks NanoRBS光谱仪的蔡司猎户座应该被证明是一个关键的
探测器物理学的工具。此外,NanoRBS的整体性能将在以下情况下得到改善
这台光谱仪改装了来自第二阶段工作的新增强型MCP。
。
英文摘要
Project Summary
A new thin film deposition technique for increasing the gain and sensitivity of existing
microchannel ion detectors was proven in a previously completed NIH phase I. An increased
Secondary Electron (SE) yield from these films was found to improve with ion doses of helium
up to > 100 Coulombs/cm2 while the electron yield from the uncoated detector first surface
decreased after 1 Coulombs/cm2. A NIH Phase II will use these films to vary elemental
composition and morphology of the first surface to increase the first hit SE yield and to prolong
the deposited layer lifetime. Detector testing will proceed with in-house ion and electron
sources.
Methods for putting these thin film coatings onto the sidewalls of the MCP (in addition to
covering the front detector surface) should increase the detector gain and substantially prolong
the detector lifetime of commercially available MCPs.
We will emphasize use of the Zeiss Orion helium ion microscope at Rutgers to perform
accelerated lifetime testing of the MCP pulse height, gain and first surface secondary electron
yield from individual pores. Elemental composition change in the first hit area of the
microchannel pore will also be determined by Nanoscale Rutherford backscattering within the
Orion and will be correlated with the lifetime and yield measurement. The combination of the
Zeiss Orion configured with the Ionwerks NanoRBS spectrometer should prove to be a crucial
tool in detector physics. In addition the overall performance of the NanoRBS will improve when
this spectrometer is retrofitted with newly enhanced MCPs from this phase II effort.
.
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Nanoparticulate Coatings Enhance Ion Detection
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批准号:10883978
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项目类别:
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资助金额:$4.0万
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财政年份:2014
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负责人:John Albert Schultz
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Biomarker Quantitation by NP-MS Tissue Imaging.
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批准号:8592448
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Biomarker Quantitation by NP-MS Tissue Imaging.
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批准号:8661740
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依托单位:
Microfocused Nanoparticulate ions to enable intracellular molecular imaging.
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批准号:8473837
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项目类别:
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资助金额:$76.06万
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财政年份:2011
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负责人:John Albert Schultz
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依托单位:
Microfocused Nanoparticulate ions to enable intracellular molecular imaging.
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批准号:8307366
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项目类别:
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资助金额:$78.03万
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财政年份:2011
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负责人:John Albert Schultz
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依托单位:
Microfocused Nanoparticulate ions to enable intracellular molecular imaging.
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批准号:8059377
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项目类别:
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资助金额:$79.99万
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财政年份:2011
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负责人:John Albert Schultz
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依托单位:
Infrared Laser Desorption Ion Mobility Mass Spectrometer
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批准号:7463890
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项目类别:
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资助金额:$19.41万
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财政年份:2007
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负责人:John Albert Schultz
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依托单位:
Infrared Laser Desorption Ion Mobility Mass Spectrometer
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批准号:7273987
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项目类别:
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资助金额:$19.94万
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财政年份:2007
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负责人:John Albert Schultz
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依托单位:
Infrared Laser Desorption Ion Mobility Mass Spectrometer
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批准号:7664534
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项目类别:
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资助金额:$19.27万
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财政年份:2007
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负责人:John Albert Schultz
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Photofragmentation MS of Ion Mobility Separated Peptides
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批准号:6643145
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依托单位:
High Mass Resolution for MALDI TOF Mass Spectrometry
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批准号:6529618
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资助金额:$37.5万
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财政年份:1998
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负责人:John Albert Schultz
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依托单位:
High Mass Resolution for MALDI TOF Mass Spectrometry
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批准号:6404266
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项目类别:
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资助金额:$45.17万
-
财政年份:1998
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负责人:John Albert Schultz
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依托单位:
HIGH MASS RESOLUTION FOR MALDI TOF MASS SPECTROMETRY
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批准号:2649433
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项目类别:
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资助金额:$9.99万
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财政年份:1998
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负责人:John Albert Schultz
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依托单位:
ULTRA SENSITIVE MULTIHIT ION DETECTOR--TOF BIOMASSPEC
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批准号:2420769
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项目类别:
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资助金额:$9.89万
-
财政年份:1997
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负责人:John Albert Schultz
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依托单位:
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资助金额:2.0万元
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批准年份:1988
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