UT Gastroenterology/Hepatology Research Training Program

项目摘要/摘要 德克萨斯大学的胃肠病学/肝脏学研究培训计划旨在生产新一代 科学领袖将重点放在了解消化和肝脏疾病上。该计划涉及各种不同的 学科大致分为两个主要领域：基础科学研究和以患者为中心的临床和 翻译研究。该培训计划接受具有内科临床培训背景的个人 医学(医学博士或医学博士/博士候选人)以及儿科学、外科或病理学专业。此外，受训人员 未经临床培训(博士生)也是我们计划的一部分。一个独特的特征是 纳入相当大比例的少数族裔受训人员，主要是西班牙裔。实习生受益于 大量潜在的导师，包括直接参与该计划的45名教师，以及非常多的 我们校园里聚集了丰富的科学研究人员。培训计划的科学基础包括 对该领域至关重要的多个领域的研究专门知识，包括6个主题：(1)免疫，(2) 微生物效应，(三)癌症生物学，(四)新陈代谢和脂肪肝，(五)营养和肥胖，(六) 发育和干细胞生物学。培训课程是灵活的，但有两个基本组成部分。首先，所有 我们的学员参加了一系列有组织的讲座，重点介绍了以下领域的前沿研究 通过博士后事务提供的胃肠病和肝病以及职业发展培训 办公室，其中包括负责任的研究行为课程以及其他相关培训 职业发展的这一阶段的经验。还设计了一些特别的培训经验来 解决个别受训人员之间的差距。除了核心教育活动外，研究方面的直接培训还包括 主要在研究导师的指导下放在基础实验室或临床研究中 一群人。一般来说，我们的学员会花2到3年的时间进行研究培训。基础科学训练 经验包括学习生物化学、生理学、分子生物学和 遗传学，以及参加正在进行的工作研讨会和国家或国际科学会议 与特定学科相关。另一方面，临床和翻译研究涉及正式的 研究设计方面的培训，包括伦理学和生物静力学，通过我们的正规培训计划 大学。最后，针对我们具有内科临床背景的学员，本次研究培训 该计划与我们在胃肠病学和肝病学方面的临床奖学金相结合，包括 至少18个月的专职临床轮换。因此，在大多数情况下，培训期将持续 被请求提供支助的六名个人的刑期为4至6年。总而言之，这个项目是 旨在培养在以下领域成为有效研究人员和学术领袖的个人 胃肠病学和肝脏病学。

PROJECT SUMMARY / ABSTRACT The UT Gastroenterology / Hepatology research training program is aimed at producing the next generation of scientific leaders focused on understanding digestive and liver diseases. The program involves a variety of disciplines broadly categorized into two main areas: basic scientific research and patient-oriented clinical and translational research. The training program accepts individuals with a clinical training background in Internal Medicine (M.D. or M.D./Ph.D. candidates), as well as in Pediatrics, Surgery or Pathology. In addition, trainees without clinical training (Ph.D. candidates) are also part of our program. One unique characteristic is the inclusion of a significant proportion of minority trainees, primarily of Hispanic origin. Trainees benefit from a vast array of potential mentors including 45 Faculty that participate directly in this program, as well as a very rich milieu of scientific investigators across our campus. The scientific base of the training program includes research expertise in multiple areas critically important to the field, including 6 main themes: (i) immunity, (ii) microbial effectors, (iii) cancer biology, (iv) metabolism and fatty liver, (v) nutrition and obesity, and, (vi) development and stem cell biology. The training curriculum is flexible, but has two basic components. First, all of our trainees participate in a structured lecture series that highlights cutting edge research in fields of gastroenterology and hepatology, and career development training offered through the postdoctoral affairs office, which includes a course in responsible conduct of research as well as other pertinent training experience for this stage of career development. A number of ad hoc training experiences are also devised to address gaps of individual trainees. In addition to core educational activities, direct training in research takes place primarily under the research mentor’s guidance in a basic laboratory or as part of a clinical research group. Typically, our trainees devote 2 to 3 years to their research training. The basic science training experience includes learning a variety of techniques in biochemistry, physiology, molecular biology and genetics, as well as participation in works-in-progress seminars and national or international scientific meetings relevant to the particular discipline. On the other hand, clinical and translational research involves formal training in study design, including ethics and biostatics, through formal training programs offered at our University. Finally, for our trainees with a clinical background in Internal Medicine, this research training program is integrated with our clinical fellowship in Gastroenterology and Hepatology, which includes a minimum of 18 months of dedicated clinical rotations. Therefore, in most instances the training period will last from 4 to 6 years for the six individuals for whom support is being requested. Altogether, this program is designed to train individuals who will be effective investigators and academic leaders in the fields of Gastroenterology and Hepatology.