Project-005

枢纽研究能力计划的主要目标是支持创新研究，并提供 研究人员进行安全、高质量转化研究的必要工具。正如RFA中所述， CTSA的组成部分将侧重于整合特殊人群（ISP）沿着参与者和临床 相互作用（PCI）。 我们的ISP核心拥有广泛的资源，可以在各个年龄组进行翻译研究， 不限于儿童、老年人、孕妇和新生儿（母胎医学），以及 西班牙裔人口。此外，UTMB在研究罕见孤儿疾病方面拥有丰富的专业知识 如卟啉症、肥大细胞病等，以及对美国目前流行病、阿片类药物使用和成瘾的研究。 行为（可选HUB）。我们专门配备了最先进的疫苗开发中心， 预防保健的关键部门。我们的目标为ISP，将利用现有的个人计划的优势， 共同扩大我们在多中心试验和服务不足社区的推广。ISP核心将是 与网络容量和信息学密切相关。 PCI核心将专注于临床研究教育。特别是，在新的方法来提高 进行高质量转化研究的安全性和效率。展望未来（目标），临床试验 将通过整合研究教练，培训和支持新的临床研究以及提供 我们的一个新的卫星演播室。与信息学数据协调中心合作， PCI核心将为新培训、监测和管理方面提供质量控制组件， 多中心临床试验。此外，UTMB继续发展成为一个更大的社区。为此， 我们将扩大UTMB的临床研究中心（CRC）的足迹和人类研究安全计划。到 为了帮助实现这些目标，PCI核心将利用临床研究办公室，临床研究 中心（CRC）以及与翻译努力和劳动力发展有着密切的联系。

The primary goal of the Hub Research Capacity program is to support innovative research and to provide the requisite tools for investigators to perform safe, high quality translational research. As outlined in the RFA, this component of the CTSA will focus on Integrating Special Populations (ISP) along with Participant and Clinical Interactions (PCI). Our ISP core has extensive resources for performing translational research in various age groups including but not limited to children, older adults, pregnant women and neonates (maternal-fetal medicine), as well as Hispanic populations. Additionally, UTMB has tremendous expertise for investigating rare, orphan diseases such as porphyria, mast cell disease etc. and research on the current US epidemic, opiate use and addictive behaviors (Optional HUB). We are exclusively equipped with a state-of-the-art vaccine development center as a critical arm of preventative care. Our Aim for ISP, will capitalize on existing individual program strengths to collectively broaden our outreach in multicenter trials and underserved communities. The ISP core will be intimately linked with Network Capacity and Informatics. The PCI core will focus its efforts on clinician research education. Specifically, on novel methods to enhance the safety and efficiency for conducting high quality translational research. Moving forward (Aims), clinical trials will be augmented by integrating study coaches, training and support for new clinical studies as well as provide investigators guidance to one of our new satellite studios. Working with Informatics Data Coordinating Center, the PCI core will provide quality control component for new training, monitoring and regulatory aspects for multi-site clinical trials. Additionally, UTMB continues to grow into a larger community area. Towards this end, we will extend UTMB’s Clinical Research Center (CRC) footprint and its human research safety program. To help accomplish these aims, the PCI core will utilize the Office of Clinical Research, the Clinical Research Center (CRC) as well as have strong links with Translational Endeavors and Workforce Development.