Washington University SummeR reseArch DIversity ProgrAm iN Cardiovascular Disease & HEmatology (RADIANCE)

项目总结/摘要 这个R25短期研究教育计划，以提高健康相关研究的多样性， “华盛顿大学（WU）心血管疾病与血液学研究项目 （辐射）”提案是对RFA-HL-22-012的回应。我们凭借丰富的经验， 现有的方案：1）NHLBI资助的“增加个人多样性方案”， 健康相关研究（PRIDE）”，重点关注全国医学代表性不足（URM）的初级 教师;和2）吴研究所公共卫生夏季研究计划（IPH-SRP）-公共和全球卫生 在过去的八年里，该项目培养了健康研究方面的本科生和健康专业学生。 我们在这些夏季研究项目和既定基础设施方面的出色记录使得 无缝的程序扩展和集成。心血管疾病（CVD）和血液系统疾病 是美国和全球发病和死亡的主要原因。诊断和治疗的差异 心血管疾病和血液病都非常普遍。我们建议招募，提供培训，指导 和职业发展和研究技能的本科生和卫生专业学生（总数：12 URM （a）来自传统上在卫生相关领域代表性不足的种族/族裔群体 B）残疾人; C）来自弱势背景，通过以下方式 目标：目标1。招募，培训，指导和吸引不同兴趣的URM学生团体 在探索研究事业，彻底的多学科方法，以推进对CVD的研究 血液系统疾病。目标2.提供严格的教学，结构化的指导和手- 研究经验，培养知识，态度和技能，在生物医学，行为和临床 research.目标3.展示和培养学员对研究、学术和专业的兴趣 心血管疾病/血液疾病的发展，并提供研究经验，将有助于告知未来 职业和培训机会。目标4.在导师和项目的指导下， 领导力，一个“顶点经验”总结介绍在该计划的最后，综合了 学员学习和研究经验。辐射的首要目标是提供创造性和高度 相关的教育活动，主要侧重于研究经验和指导活动，以提高 生物医学研究人员的多样性。该提案的目标与NHLBI的科学优先事项相一致 1）提供广泛的CVD/血液病教学和研究培训; 2）提供科学的 为学员提供研究基金; 3）确保公平和包容性的方案获得和参与的不同 美国人口。NHLBI资助的WU计划和指导教师将为学员提供出色的经验。 我们乐观地认为，这一建议将有助于提高研究人员在以下领域的多样性： NHLBI的重要性使命。

PROJECT SUMMARY/ABSTRACT This R25 Short-Term Research Education Program to Enhance Diversity in Health-Related Research titled “Washington University (WU) SummeR reseArch DIversity ProgrAm iN Cardiovascular Disease & HEmatology (RADIANCE)” proposal is in response to RFA-HL-22-012. We build upon our extensive experience with two currently-existing programs: 1) NHLBI-funded “Programs to Increase Diversity among Individuals Engaged in Health-Related Research (PRIDE)”, which focuses on nationally underrepresented in medicine (URM) junior faculty; and 2) WU Institute for Public Health Summer Research Program (IPH-SRP) – Public and Global Health Track that has trained undergraduate and health professional students in health research for past eight years. Our excellent track-record with these summer research programs and established infrastructure allows for seamless program expansion and integration. Cardiovascular disease (CVD) and Hematologic Disorders are leading causes of morbidity and mortality in the US and globally. Disparities in diagnosis and treatment of both CVD and Hematologic Disorders are highly prevalent. We propose to recruit, provide training, mentoring and career development and research skills to undergraduate and health professional students (total: 12 URM trainees/year) who are individuals: A) from racial/ethnic groups traditionally underrepresented in health-related sciences on a national basis; B) with disabilities; and C) from disadvantaged backgrounds, through the following OBJECTIVES: Objective 1. To recruit, train, mentor, and engage a diverse URM students group with interests in exploring research careers, thorough a multidisciplinary approach necessary to advance research on CVD and Hematologic Disorders. Objective 2. To provide rigorous didactics, structured mentoring and hands- on research experiences that foster knowledge, attitudes, and skills in biomedical, behavioral, and clinical research. Objective 3. To expose and nurture trainee interests in research, academic and professional development in CVD/Hematologic Disorders and to provide research experiences that will help inform future career and training opportunities. Objective 4. To prepare, under guidance from mentors and program leadership, a “capstone experience” summary presentation at the end of the program that synthesizes the trainee learning and research experience. The overarching goal of RADIANCE is to provide creative and highly relevant educational activities with primary focus on research experiences and mentoring activities for enhancing diversity of the biomedical research workforce. The goals of this proposal align with scientific priorities of NHLBI to: 1) provide broad CVD/Hematologic Disorders teaching and research training; 2) provide scientific research foundation for trainees; 3) ensure equitable & inclusive program access and participation of diverse US populations. NHLBI-funded WU Program & Mentoring Faculty will offer excellent experiences for mentees. We are optimistic that this proposal will help enhance the diversity of the research workforce in areas of importance to the NHLBI mission.