Oregon Clinical and Translational Science Institute

___ 俄勒冈州的生物医学研究机构是杰出的，并准备在 临床/转译研究。我们建议成立俄勒冈州临床和翻译科学研究所 (OCTSI)。OCTSI将从根本上改变生物医学研究，为 临床/转译研究。它将利用现有的优势，消除速度和 研究的增长。OCTSI的核心是俄勒冈州健康和科学公司之间的牢固合作伙伴关系 大学(OHSU)和Kaiser Permanente健康研究中心(KPCHR)将一个 强大的生物医学研究型大学和以实践为基础的创新研究中心 患者人数众多。这种协作为跨领域扩展提供了独特的机会 人类研究的最新进展，为人类健康的重大进展奠定了基础。 俄勒冈州临床和转克隆研究的转变通过以下方式得到加强： ？对八达通社的强有力的机构支持，表现为重大的行政改革以及 承诺大量财政和空间资源 ？OHSU和KPCHR的学术人员全力支持OCTSI倡议和制定 强大的多学科OCTSI领导团队 ？合并资源，形成临床/转化性研究的协调基础设施 ·与社区的密切联系以及该区域对人类研究议程的参与 我们确定了OCTSI的三大目标，并提出了影响深远、明确可行的建议 实现这些目标的方法。我们将创建一个学术之家(OCTSI)专门致力于 临床/转化性研究学科，2)培养高素质、跨学科的新干部 调查人员通过强大的、多样化的教育课程，3)创建“研究共享空间”-a 协调的核心研究工具基础设施，极大地扩展了研究机会，并提供了 统一、有效的接入手段。 有特别的机会加快以社区为基础的儿科和儿童健康方面的进展 研究和人类遗传学。

___ Biomedical research institutions in Oregon are outstanding, and are prepared for a major expansion in clinical/translational investigation. We propose to form the Oregon Clinical and Translational Science Institute (OCTSI). The OCTSI will fundamentally change biomedical researchto create a vibrant academichome for clinical/translational investigation. It will leverage existing strengths and remove barriers to the pace and growth of research. At the heart of the OCTSI is a robust partnership between Oregon Health & Science University (OHSU) and Kaiser Permanente's Center for Health Research (KPCHR) that brings together a strong biomedical research university and an innovative practice-based research center associatedwith a large patient population. The collaboration provides unique opportunities for expansion across the spectrum of human investigation, and sets the stage for major advances in human health. Transformation of clinical and translatlonal research in Oregon is enhanced by: ¿ Robust institutional support for the OCTSI, manifest by significant administrative change as well as the commitment of substantial financial and space resources ¿ Academic faculties at OHSU and KPCHR that fully support the OCTSI initiative and the development of a strong, multidisciplinary OCTSI leadership team ¿ Merging of resourcesto form a coordinated infrastructure for clinical/translational research ¿ Strong ties to the community and the involvement of the region in the human researchagenda We have identified three major goals for the OCTSI, and propose far-reaching, explicit andfeasible approaches to achieve them. We will 1) Create an academic home (the OCTSI) specifically devoted to the discipline of clinical/translational research, 2) Nurture a new cadre of highly-trained, interdisciplinary investigators through a strong, diverse educational curriculum, 3) Create a "Research Commons"- a coordinated infrastructure of core research tools that greatly expands research opportunities and provides a unified, effective means for their access. There are particular opportunities to accelerate progress in pediatric and child health, community based research, and human genetics.