SCIENTIFIC ANIMATION TOOLS FOR BIOMEDICAL APPLICATIONS

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 国家高分子成像中心（NCMI）寻求与NBCR合作，将NCMI的科学动画与集成库（SAIL）迁移到NBCR的可视化编程环境Vision。 NCMI开发的这些工具已经产生了许多用于各种关键应用的可视化效果，例如评估电子低温显微镜3-D重建在不同细化阶段的有效性;在大分子背景下分割蛋白质组分;在提取的分子组分图中发现结构特征，如α螺旋和β折叠;制作动画以模拟复杂的生物现象;制作演示复杂结构的动画;为出版物和演示生成图形;帮助合作者理解NCMI的产品;并为同行级实验室提供可比较的可视化环境。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The National Center for Macromolecular Imaging (NCMI) seeks to collaborate with NBCR by migrating NCMI's Scientific Animation & Integration Library (SAIL) to NBCR's visual programming environment Vision. These tools developed by NCMI have produced numerous visualizations used in various critical applications such as to evaluate the validity of electron cryomicroscopy 3-D reconstructions at different refinement stages; segmenting protein components in a macromolecular context; discovering structural features such as alpha helices and beta sheets in the extracted molecular component maps; production of animations to model complex biological phenomena; production of animations for presentations of complex structures; generation of graphics for publications and presentations; assisting collaborators in understanding NCMI's products; and providing comparable visualization environments to peer level laboratories.