Research Training in Gastroenterology

 描述(由申请人提供)：这是一个培训计划的续展申请，为期6-10年，旨在培养成人胃肠病领域研究的前沿研究人员。受训者为博士后水平，博士和博士混合提供两年支持，每年总共申请3笔津贴。对于所有受训人员，该计划都将重点放在流行病学和卫生服务研究上，其基本原理是迫切需要“从工作台到床边”的转化性研究。还需要“床边对临床”，或“疗效对有效性，以及以患者为中心的比较有效性”的转化性或结果研究。这些导师(2名医学博士、6名医学博士/时速、1名医学博士/博士和1名博士)代表了一个由贝勒医学院(BCM)和德克萨斯大学健康科学中心不同部门的经验丰富的研究人员组成的多学科小组。他们的研究涵盖了广泛的临床研究领域，包括流行病学(包括临床、分子、遗传和微生物组)、卫生服务研究、决策和与几种消化疾病相关的实施研究。所有导师研究小组都有充足的资金。现有的教职员工有出色的指导历史，在互动和参与我们的培训计划活动方面也有出色的记录。项目主管，医学博士，公共卫生硕士，维护项目的最终权威，并管理日常运作。他由一名副项目主任(Thomas Giordano，医学博士，公共卫生硕士)协助。自培训计划开始以来，领导层保持稳定。重大行政决策(例如，学员的选择)由一个遴选委员会处理，该委员会包括项目主任、副主任和其他三名项目教职员工。受训者有单独的研究指导委员会，必须准备一份书面研究提案，并向研究委员会进行辩护，并进行定期审查，其中包括学术和职业评估。学员被要求参加每周一次的系列研究研讨会和每月一次的期刊俱乐部。所有受训人员必须出席这些会议。学员是从BCM现有的竞争激烈的申请者池中挑选出来的。在过去的4年里，该项目的录取竞争非常激烈，所有可供选择的都是高素质的候选人。受训人员表现良好，前两名博士后毕业生获得了公共卫生硕士学位，仍留在学术界，每个人都有几篇第一作者的原创研究论文发表在影响较大的期刊上，并发表了几次全国研究报告。目前的建议包括几个旨在丰富和加强现有计划的新功能，包括新的导师，每年三次的科学社会与儿科GI培训计划相结合，以及针对MD实习生的两年临床科学家培训计划。

 DESCRIPTION (provided by applicant): This is the renewal application for Years 6-10 of a training program designed to produce investigators at the cutting edge of research in the area of adult gastroenterology. Trainees are at the postdoctoral level and a mixture of MDs and PhDs supported for 2 years for a total request of 3 stipends/yr. For all trainees, the program has placed strong emphasis on epidemiology and health services research, the rationale being the critical need for "bench to bedside" translational research. There is also a need for "bedside to clinic", or "efficacy to effectiveness, and patient centered comparative effectiveness" translational or outcomes research. The mentors (2 MDs, 6 MD/MPH, 1 MD/PhD and 1 PhD) represent a multidisciplinary group of experienced investigators from various departments at Baylor College of Medicine (BCM) and the University of Texas Health Science Center. Their research covers broad areas of clinical research including epidemiology (including clinical, molecular, genetic, and microbiome), health services research, decision making, and implementation research related to several digestive disorders. All mentors research groups are well funded. Existing faculty members have outstanding mentoring histories, and excellent track records of interaction and participation in our training program activities. The Program Director, Hashem B El-Serag, MD, MPH, maintains ultimate authority for the program and manages day-to-day operations. He is assisted by an Associate Program Director (Thomas Giordano, MD, MPH). The leadership remains stable since the start of the training program. Major administrative decisions (e.g., selection of trainees) are handled by a selection Committee, which includes the Program Director, Associate Director, and three other program faculty. The trainees have individual research mentoring committees, must prepare a written research proposal to be defended to the research committee, and have periodic reviews that include academic and career assessment. Trainees are required to attend a weekly research seminar series and a monthly journal club. All trainees must present at these meetings. Trainees are selected from a highly competitive applicant pool that already exists at BCM. Over the past 4 years, admission into the program has been very competitive, and all available were filled with high quality candidates. The trainees have performed well with the first two post-doctoral graduates obtaining Masters degrees in Public Health, remaining in academia, and each has several first author original research papers published in high impact journals and several national research presentations. The current proposal includes several new features designed to enrich and enhance the existing program including new mentors, thrice yearly scientific social combined with the pediatric GI training program and a two year Clinical Scientist Training Program for MD trainees.