Research Training in Gastroenterology

 描述(由申请者提供)：本提案请求支持1999年建立的胃肠病学学术研究培训计划的继续。项目主任是哈佛医学院(HMS)医学教授、贝丝以色列女执事医学中心(BIDMC)胃肠病奖学金项目主任Ciarán P Kelly博士。要求继续为每年四个受训人员职位提供支助，每个受训人员将在培训方案中工作两到三年。受训者将获得医学博士、博士或医学博士学位，并具有相关科学学科的背景。遴选的主要标准将包括教育成就、在生物医学研究方面表现出的成就和能力，以及致力于在与消化疾病相关的研究领域发展学术事业。培训将主要包括根据受训者的需求、人才和职业目标开发的与健康相关的基础科学、临床研究项目或转化研究的指导性研究计划。主要的培训地点是BIDMC的胃肠病和肝病科。BIDMC的其他培训地点将设在内分泌学、免疫学、肾脏病、系统生物学、疫苗和血管生物学等部门。外部站点将设在哈佛公共卫生学院(流行病学和生物统计学)、波士顿退伍军人管理局(VA)医学中心(胃肠病学)和马萨诸塞州总医院(MGH)(儿科胃肠病学)。BIDMC、哈佛医学院、哈佛公共卫生学院、波士顿退伍军人管理局、麻省理工学院以及哈佛大学的“催化剂”计划(哈佛临床和转化科学奖)都提供各种设施和研究中心。所有地点都位于很近的位置，便于持续的互动。T32教员在许多领域进行与胃肠道相关的研究，这些研究可归类为四个一般主题：肝损伤与纤维化、感染与免疫、血管生物学和上皮生物学。培训计划的基石在于我们资深和有成就的教职员工提供的个人指导。此外，还有一个由研究研讨会和讲座、期刊俱乐部、实验室演示和持续的职业指导组成的有组织的项目。有兴趣的学员将被鼓励参加高级培训，包括在适当的情况下获得硕士学位(公共卫生硕士或医学硕士)，或在对其研究职业发展重要的领域参加非学位课程。该计划的核心重点是使有才华和奉献精神的年轻科学家能够在学术医学领域推进他们的职业生涯，并最终成为研究与消化健康和疾病相关的问题的多产和独立的研究人员。

 DESCRIPTION (provided by applicant): This proposal requests support for the continuation of a research training program in academic Gastroenterology that was established in 1999. The Program Director is Dr. Ciarán P Kelly, Professor of Medicine, Harvard Medical School (HMS) and Fellowship Program Director in Gastroenterology at Beth Israel Deaconess Medical Center (BIDMC). Continued support is requested for four trainee positions per year with each trainee spending two to three years in the training program. Trainees will have received an MD, PhD or MD-PhD degree and have a background in relevant scientific disciplines. The main criteria for selection will include educational achievements, demonstrated achievement and ability in biomedical research and a commitment to developing an academic career in research related to digestive disorders. Training will consist primarily of a mentored research program in health-related basic science, clinical research projects or translational research studies developed according to the needs, talents and career goals of the trainee. The main training site is the Gastroenterology and Hepatology Division at BIDMC. Additional BIDMC training sites will be in the Divisions of Endocrinology, Immunology, Nephrology, Systems Biology, Vaccines and Vascular Biology. External sites will be at the Harvard School of Public Health (Epidemiology & Biostatistics), the Veterans Administration (VA) Medical Center, Boston (Gastroenterology) and the Massachusetts General Hospital (MGH), (Pediatric Gastroenterology). A wide range of facilities and research cores are available at BIDMC, Harvard Medical School, the Harvard School of Public Health, the Boston VA and the MGH as well as through the Harvard "Catalyst" program (Harvard Clinical and Translational Science Award). All sites are situated in close proximity facilitating ongoing interactions. The T32 faculty performs GI-related research in many areas that can be grouped into four general themes: Liver Injury & Fibrosis, Infection & Immunity, Vascular Biology and Epithelial Biology. The cornerstone of the training program lies in the individual mentorship provided by our senior and accomplished faculty. This is augmented by a structured program of research seminars and lectures, journal clubs, laboratory presentations and ongoing career mentoring. Interested trainees will be encouraged to pursue advanced training including a Masters degree, if appropriate, (Masters in Public Health or Masters in Medical Science) or to take non-degree classes in areas important to their research career development. The central focus of the program is to enable talented and dedicated young scientists to advance their careers in academic medicine and eventually to become productive and independent investigators researching questions relevant to digestive health and disease.