Probing metal coating composition and leachability on virus stability

Aereus是一家位于安大略省的公司，将Aereus Shield商业化。他们的专利工艺生产耐用，有吸引力的涂层证明杀死接触有害细菌。在加拿大，Aereus Shield作为抗菌剂销售，仅用于I类和II类医疗器械。他们的涂层提供了针对常见医院病原体的经济有效的干预措施，是高接触公共表面的理想解决方案。然而，微生物病原体并不是唯一值得关注的微生物。病毒可以在表面存活，并可能导致感染在医院等高风险环境中传播。通过这项资助，更深入地了解了Aereus Technologies公司开发的病毒和新型材料涂层之间相互作用的机制。已经开发了一种模型包膜病毒系统，通过Aucoin实验室和Aereus之间先前举行的NSERC合作伙伴关系来探测Aereuscoating。这个后续项目旨在验证令人兴奋的发现，即这些新型材料可能具有自我灭菌能力。Aereus和Aucoin将通过加深对Aereus材料的理解来解决医院感染的问题，然后利用这种理解来更好地设计新产品。

Aereus is an Ontario-based company commercializing Aereus Shield. Their patented process produces adurable, attractive coating proven to kill harmful bacteria on contact. In Canada, Aereus Shield is marketed asan antimicrobial for use exclusively on Class I and Class II medical devices. Their coating provides acost-effective intervention against common hospital pathogens and is an ideal solution for high touch publicsurface. However, microbial pathogens are not the only microbes of concern. Viruses can survive on surfacesand can lead to the spread of infection in high risk settings such as hospitals. Through this grant, a greaterunderstanding of the mechanisms at play in the interaction between viruses and novel material coatingsprepared by Aereus Technologies. A model envelope virus system has been developed to probe the Aereuscoating through a previously held NSERC partnership between the Aucoin Lab and Aereus. This follow-upproject aims to verify exciting findings that these novel materials may be self-sterilizing. Together, Aereus andAucoin will tackle the problem of nosocomial infections by deepening an understanding of Aereus materialsand then utilizing this understanding to better design novel products.