Development and optimization of downstream process for recovery of natural aldehydes from fermentation media

Ardra Inc.是一家可持续生产高纯度天然成分的生物技术公司，适用于天然香料，香水和化妆品配方。Ardra的产品使用天然糖发酵生产，与传统的植物提取相比，具有显著的成本和可持续性优势。此外，由于产品不依赖于植物原料，它们的供应是稳定的，没有季节性变化。发酵生产这些化学物质的一个困难是在发酵完成后从发酵副产物的混合物中高效和高纯度地分离出所需的产物。因此，Ardra正在与Seneca生物科学与应用化学学院的Jamie Cote教授和David Guevara教授合作。Cote教授在有机化学品和药物的分离和纯化方面拥有超过5年的经验，Guevara教授在天然产物分离和分析方面拥有超过10年的经验。与SBSAC的研究助理一起，Cote教授和Guevara教授将与Ardra密切合作，了解现有的净化工艺，并设计和优化一种新的净化工艺，这种工艺将更具成本效益，同时也提供比现有方法更少浪费的更高纯度的产品。由此产生的过程将直接实施到Ardra的生产线上，为公司提供直接的利益。

Ardra Inc. is a biotechnology company that manufactures high-purity natural ingredients sustainably, which are suitable for use in natural flavours, perfumery and cosmetics formulations. Ardra's products, produced using fermentation of natural sugars, offer significant cost and sustainability advantages over traditional plant-based extractions. Additionally, since the products do not rely on botanical raw material, their supply is stable and devoid of seasonal variations. One difficulty in fermentation to produce these chemicals is the efficient and high-purity isolation of the desired product from the mixture of fermentation byproducts after fermentation is complete. As a result, Ardra is collaborating with Professor Jamie Cote and Professor David Guevara, from the School of Biological Sciences and Applied Chemistry (SBSAC) at Seneca. Professor Cote has over 5 years of experience in separations and purifications or organic chemicals and pharmaceuticals, and Professor Guevara has over 10 years of experience in natural products separations and analysis. Along with their research assistants from SBSAC, Professor Cote and Guevara will work closely with Ardra to understand the existing purification process and design and optimize a new purification procedure that will be more cost effective, but also provide a higher-purity product with less waste than the existing method. This resulting process will be directly implemented into Ardra's production line to provide immediate benefit to the company.