Optimization of Fermentation and Downstream Process for the Production of Lactobacillus equi Probiotics

CanBiocin是世界上唯一真正的原始益生菌菌株来源，被广泛认为是特定物种动物和牲畜益生菌开发的领导者。CanBiocin总部位于埃德蒙顿，通过与益生元成分的精心组合，将物种特异性益生菌的有益影响最大化，专注于生物后代谢产物的产生，以支持动物的健康和保健。CanBiocin希望以科学为后盾，为宠物和牲畜提供最佳健康，然而，当涉及到商业发酵和作为单个物种的规模扩大时，一种尺寸并不适合所有人-特定的益生菌是多样的，并具有它们自己独特的特性。在CanBiocin的背景下，马被归类为伴侣动物，而商业客户对特定物种的益生菌感兴趣。为使其具有商业可行性，需要进一步优化马蹄脂菌的发酵和下游工艺，以提高产品的产率和纯度。在合作中，CanBiocin和兰顿学院将专注于确定最佳实践，这些实践可以转化为商业规模的生产和收获马乳杆菌作为一个物种-特定益生菌用于支持动物健康和伴侣马以及表演马的健康。该合作项目的成功将使CanBiocin加快其新产品的商业化，因为市场需求与商业客户确认和等待输送这种特殊成分来支持微生物组健康。预计CanBiocin的业务将扩大，以适应额外的产品混合和包装，从而导致额外的4个全职职位。此外，这些职位将在产品发布期间保留，以支持进一步的产品开发和新物种特异性菌株鉴定和分类。

The world's only source of true ancestral probiotic strains, CanBiocin is widely recognized as a leader inspecies-specific animal and livestock probiotic development. Based in Edmonton, CanBiocin maximizes thebeneficial impact of species-specific probiotics by careful combination with prebiotic ingredients to focus onpost-biotic metabolite production to support animal health and wellness.CanBiocin wants the best health for pets and livestock that is backed by science, however, one size does not fitall when it comes to commercial fermentation and scale up as individual species-specific probiotics are diverseand have their own unique characteristics. Horses are classified as a companion animal in CanBiocin's contextand a species-specific probiotic is of immediate interest for commercial customers. To be commercially viable,the Ligilactobacillus equi (L.equi) needs further optimization of the fermentation and downstream process toimprove the product yield and purity. In collaboration, CanBiocin and Lambton College will focus ondetermining best practices that can translate into commercial-scale production and harvest of L.equi as aspecies-specific probiotic for use in supporting animal health and wellness in companion as well asperformance horses.The success of this collaborative project will allow CanBiocin to speed up their commercialization of this newproduct as there is market demand with commercial customers confirmed and awaiting delivery of thisspecialized ingredient to support microbiome health. It is anticipated that CanBiocin's operation will expand toaccommodate the additional product blending and packaging, thus leading to an additional 4 full-timepositions. Furthermore, these positions will be retained during product launch to support further productdevelopment and new species-specific strain identification and classification.