Acquisition of a 500 MHz NMR Spectrometer

核磁共振（NMR）光谱是化学家用来研究分子结构的最有力的工具。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。获得最先进的核磁共振光谱学对于正在进行前沿研究的化学家和生物学家来说是必不可少的。纽约州立大学石溪分校化学系将利用化学仪器项目和仪器与仪器开发项目的这笔资金，帮助获得一台高场核磁共振光谱仪。此次收购将加强的化学和生物研究领域包括：1)生理活性脂质的合成与生物化学；多肽和碳水化合物2)基于胆汁酸的分子受体3)金属蛋白活性位点合成类似物和异相金属硫化物催化剂的核磁共振研究4)位点特异性酶和DNA修饰5)杂环合成和分子识别。

Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to the chemist for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectroscopy is essential to chemists and biologists who are carrying out frontier research. The Department of Chemistry of SUNY at Stony Brook will use this award from the Chemical Instrumentation Program and the Instrumentation and Instrument Development Program to help acquire a high-field NMR spectrometer. The areas of chemical and biological research that will be enhanced by the acquisition include: 1) Synthetic and biological chemistry of physiologically-active lipids, polypeptides and carbohydrates 2) Molecular receptors based on bile acids 3) NMR studies of synthetic anologs for the active sites of metalloproteins and heterogeneous metal-sulfide catalysts 4) Site-specific enzyme and DNA modification 5) Heterocyclic synthesis and molecular recognition.