Acquisition of an NMR Spectrometer for Undergraduate and Graduate Research

高场核磁共振波谱仪是唯一最重要的 有机和无机化学家可用于结构的工具 决心，它正在成为一个非常有用的 分析化学家和生物化学家技术。 化学共享仪器计划（Chemistry Shared Instruments Program） 将帮助化学系在大学的 太平洋公司获得一台高场核磁共振光谱仪。 的NMR 光谱仪将用于以下研究主题： 1. DNA-多胺和DNA-组蛋白相互作用的NMR研究 2. 多核大环化合物的合成与表征 系统 3. 磷酰自由基与不饱和脂肪酸的反应 二硫化物 4. 含氮化合物的合成及构象研究 碳水化合 5. 含乙酰化和乙酰化的酶抑制剂的合成 脱乙酰多胺

The high field NMR Spectrometer is the single most important tool available to organic and inorganic chemists for structure determination, and it is becoming a significantly useful technique for analytical chemists and biochemists. This award from the Chemistry Shared Instrumentation Program will help the Department of Chemistry at University of the Pacific acquire a high field NMR Spectrometer. The NMR Spectrometer will be used in the following research topics: 1. NMR Studies of DNA-Polyamine and DNA-Histone Interactions 2. Synthesis and Characterization of Macrocyclic Multinuclear Systems 3. Reactions of Phosphoranyl Radicals with Unsaturated Disulfides 4. Synthetic and Conformational studies of Nitrogen Containing Carbohydrates 5. Synthesis of Inhibitors of Enzymes with Acetylated and Deacetylated Polyamines