Acquisition of 500 mHz NMR Instrument

购置 500 mHz NMR 仪器

• 批准号: 9402529
• 负责人: Arthur Watterson
• 金额: $ 34.7万
• 依托单位: University of Massachusetts Lowell
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-07-15 至 1996-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9402529&HistoricalAwards=false
• 关键词: Acquisition; 500; mHz; NMR; Instrument

Funds are provided to The Center for Advanced Materials (CAM) to acquire a 500-MHz NMR instrument for research programs of more than 50 faculty, staff and graduate students within the University. The availability of this instrument will allow the Center to expand and develop substantial interdisciplinary research in materials. Currently, no capability for 500-MHz studies exists at the institution. Research initiatives just underway include studies of: 1)synthetic analogues of natural poly(beta- hydroxyalkanoates); 2) stereochemical and repeat unit sequence analysis; 3) characterization of rigid-rod like site-selective Chitosan derivatives; 4) characterization of biodegradation products; 5) characterization of fermentation reactions and products; 6) reversible association/gelation of amphiphilic cation-anion polymers; 7)relative strength of intraand intermolecular ionic interactions; 8) well-defined blockgraft- and functional polymers by living cationic polymerization; 9)initiation via haloboration in living cationic polymerization; 10) syntheses and characterization of biotinylated copolymers of thiophene and nonlinear optical chromophore substituted copolymers of thiophene which are precursors for monolayer, photovoltaic and biosensor applications; 11) syntheses and characterization of novel polydiacetylenes for second and third order nonlinear optical applications; 12) syntheses and characterization of guest-host, sol-gel, and interpenetrating polymer network(IPN) systems for NLO applications; 13) NMR studies of polyacetylenes; 14) and studies of chemical shifts, coupling constant, and molecular structures of selenium and tellurium compounds. Funds are provided to The Center for Advanced Materials (CAM) to acquire a 500-MHz NMR instrument for research programs of more than 50 faculty, staff and graduate students within the University. The availability of this instrument will allow the Center to expand and develop substantial interdisciplinary research in m aterials. Currently, no capability for 500-MHz studies exists at the institution. The greater chemical shift dispersion of the high field instrument is advantageous for characterization of materials, particularly polymer stereochemistry, sequencing and biological macromolecules. Such information is extremely valuable for determining mechanisms of polymerization and degradation and macromolecular interactions. In addition, the four-fold gain in sensitivity will permit studies of low sensitivity nuclei and/or dilute spin systems that are currently either inaccessible or accessible only through the preparation of isotopically enriched materials.

资金提供给先进材料中心（CAM），以获得一台500 MHz的核磁共振仪器，用于大学内50多名教职员工和研究生的研究项目。该仪器的可用性将使该中心能够扩大和发展大量的跨学科材料研究。 目前，该机构没有进行500兆赫研究的能力。正在进行的研究计划包括：1）天然聚乙烯的合成类似物（β-羟基链烷酸酯）; 2）立体化学和重复单元序列分析; 3）刚性棒状位点选择性壳聚糖衍生物的表征; 4）生物降解产物的表征; 5）发酵反应和产物的表征; 6）两亲性阳离子-阴离子聚合物的可逆缔合/凝胶化; 7）分子内和分子间离子相互作用的相对强度; 8）通过活性阳离子聚合的明确的嵌段接枝和功能聚合物; 9）在活性阳离子聚合中通过卤代硼化引发; 10）作为单层、光伏和生物传感器应用的前体的噻吩的生物素化共聚物和噻吩的非线性光学发色团取代的共聚物的合成和表征; 11）用于二阶和三阶非线性光学应用的新型聚二乙炔的合成和表征; 12）用于NLO应用的客体-主体、溶胶-凝胶和互穿聚合物网络（IPN）系统的合成和表征; 13）聚乙炔的NMR研究; 14）硒和碲化合物的化学位移、耦合常数和分子结构的研究。 资金提供给先进材料中心（CAM），以获得一台500 MHz的核磁共振仪器，用于大学内50多名教职员工和研究生的研究项目。该仪器的可用性将使该中心能够扩大和发展材料的实质性跨学科研究。 目前，该机构没有进行500兆赫研究的能力。高场仪器的更大的化学位移色散有利于材料的表征，特别是聚合物立体化学、测序和生物大分子。这些信息对于确定聚合和降解以及大分子相互作用的机制是非常有价值的。此外，灵敏度提高四倍，将使人们能够研究目前无法获得或只能通过制备同位素富集材料才能获得的低灵敏度核和/或稀释自旋系统。