NMR Facility Upgrade

核磁共振设施升级

• 批准号: 9601658
• 负责人: A. Richard Chamberlin
• 金额: $ 24万
• 依托单位: University of California-Irvine
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-09-01 至 1998-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9601658&HistoricalAwards=false
• 关键词: NMR; Facility; Upgrade

9601658 Chamberlin University of California Irvine This award from the Academic Research Infrastructure (ARI) Program will assist the Department of Chemistry at the University of California at Irvine upgrade the existing 500 MHz and 300 MHz NMRs. This equipment will enhance research in a number of areas including the following: (1) signaling mechanisms in the central nervous system (2) new models for monodisperse silica-supported catalysts (3) strategies for the formation of peptide b-sheets (4) new reactions and strategies that allow the efficient assembling of complex molecules with high stereo- and enantiocontrol (5) polyene macrolide antibiotics (6) synthetic methodology/natural product synthesis and polymer syntheses/materials chemistry (7) research of compounds which contain indole rings coupled at the 2 position, and (8) new reactions of silacyclopropanes. Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research. The results from these NMR studies are useful in the areas such as polymers, catalysis, and in biology.

9601658 Chamberlin University of加州尔湾分校学术研究基础设施（ARI）计划的这一奖项将帮助位于尔湾的加州大学化学系升级现有的500 MHz和300 MHz NMR。这些设备将加强若干领域的研究，包括：（1）中枢神经系统中的信号传导机制（2）单分散二氧化硅负载催化剂的新模型（3）形成肽b片层的策略（4）允许高效组装具有高度立体和对映体控制的复杂分子的新反应和策略（5）多烯大环内酯抗生素（6）合成方法学/天然产物合成和高分子合成/材料化学（7）含有2位偶联吲哚环的化合物的研究，和（8）硅杂环丙烷的新反应。 核磁共振（NMR）光谱是化学家用来阐明分子结构的最有力的工具。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。 对于从事前沿研究的化学家来说，使用最先进的NMR光谱分析技术是必不可少的。 这些NMR研究的结果在聚合物、催化和生物学等领域都很有用。