2001 CSHL Conference on Eukaryotic mRNA Processing to be held August 22-26, 2001, Cold Spring Harbor New York

冷泉港实验室会议“真核mRNA加工”将于2001年8月22日至26日举行，科学家将聚集在一起研究mRNA加工、运输和周转的各个方面。最近在这些领域取得了重大进展，这次会议将是一个及时的事件，讨论最新的未发表的结果和交流思想，从而促进这一迅速发展的领域的新发展。2001年的会议是该会议的第三次会议，每隔一年在冷泉港实验室举行。最近的一次会议于1999年8月25日至29日举行，吸引了国际上277名科学家，他们正在积极研究真核细胞中信使RNA成熟的各个方面，使用遗传，生物化学，分子和细胞生物学方法。与前几次会议一样，主要重点将放在mRNA成熟的核事件上，特别是mRNA剪接和聚腺苷酸化，但范围现在将扩大到包括mRNA的历史对其最终生物命运的影响。会议形式将包括七次全体会议和三次海报会议。将根据提交的摘要挑选全体会议的发言者，这将鼓励年轻科学家积极参与。涵盖的主要主题将包括mRNA剪接和3 '端加工的催化机制;通过选择性剪接和多聚腺苷酸化对基因表达的发育和细胞类型特异性调节; snRNP和hnRNP颗粒的结构和功能;加工机制的组装; mRNA运输和周转;以及RNA加工反应的定位和动力学。信使RNA（mRNA）是一种携带基因编码的信息的分子，其形式可供细胞使用。mRNA的各种类型的加工使细胞能够根据细胞的需要调节它们的使用。 mRNA的正确加工对其功能至关重要。这次会议将有助于传播目前关于这一重要专题的研究成果，并将促进和推动进一步的进展。 该奖项将使在美国工作的研究生，博士后研究员和年轻的研究人员参加会议。

The Cold Spring Harbor Laboratory Conference "Eukaryotic mRNA Processing", to be held August 22 - 26, 2001, will convene scientists studying various aspects of mRNA processing, transport and turn-over. Major advances have recently been made in these areas, and the conference will be a timely event for discussing the latest unpublished results and exchanging ideas, thereby fostering new developments in this rapidly moving field. The 2001 conference is the third meeting of this conference, which is held every other year at Cold Spring Harbor Laboratory. The most recent meeting was held on August 25-29, 1999, and attracted internationally 277 scientists who are actively investigating various aspects of messenger RNA maturation in eukaryotic cells, using genetic, biochemical, molecular, and cell biological approaches. As in the previous meetings, a major focus will be on nuclear events in mRNA maturation, particularly mRNA splicing and polyadenylation, but the scope will now be expanded to encompass the impact of the history of an mRNA on its ultimate biological fate. The meeting format will consist of seven plenary sessions and three poster sessions. Speakers in the plenary sessions will be selected on the basis of the submitted abstracts, which will encourage active participation by junior scientists. The main topics covered will include catalytic mechanisms of mRNA splicing and 3'-end processing; developmental and cell-type specificregulation of gene expression by alternative splicing and polyadenylation; structure and function of snRNP and hnRNP particles; assembly of the processing machineries; mRNA transport and turnover; and localization and dynamics of RNA processing reactions. A messenger RNA (mRNA) is a molecule that carries the information encoded by a gene in a form that is useable by the cell. Various types of processing of mRNA's enable cells to regulate their use according to the cells' needs. Proper processing of mRNA's is essential for their functioning. This meeting will help disseminate current research findings on this vital topic and will stimulate and facilitate further advances. This award will enable graduate students, postdoctoral fellows, and young investigators working in the United States to attend the meeting.