MRI: Acquisition of an LC/MS system for Research in Chemistry and Biochemistry

MRI：购买 LC/MS 系统用于化学和生物化学研究

• 批准号: 0116181
• 负责人: David J. Brook
• 金额: $ 13.09万
• 依托单位: University of Detroit Mercy
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-15 至 2004-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0116181&HistoricalAwards=false
• 关键词: MRI; Acquisition; LC; MS; system

With this award from the Major Research Instrumentation (MRI) Program, the Department of Chemistry and Biochemistry at the University of Detroit-Mercy will acquire a liquid chromatograph with mass spectrometric detection. This versatile system includes a photodiode array detector and a quadrupole mass spectrometry detector with atmospheric pressure electrospray and chemical ionization sources. This equipment will enhance research in a number of areas including characterization of verdazyl free radicals, isoflavones and their metabolites and modified peptides. Liquid chromatography with mass spectrometric detection (LCMS) is an extremely powerful technique used for the separation and analysis of complex mixtures. This instrument will substantially strengthen scientific research at this primarily undergraduate institution. The LCMS will also be used in advanced courses.

底特律大学梅西分校的化学和生物化学系将从主要研究仪器(MRI)计划获得这一奖项，并将获得一台具有质谱学检测功能的液相色谱仪。该系统包括一个光电二极管阵列检测器和一个带有大气压电喷雾和化学电离源的四极质谱计检测器。该设备将加强一些领域的研究，包括绿豆根自由基、异黄酮类及其代谢物和修饰多肽的表征。液-质联用检测(LC-MS)是一种用于复杂混合物的分离和分析的非常强大的技术。这一仪器将大大加强这所以本科为主的机构的科学研究。学习管理系统也将用于高级课程。