Acquisition of NMR Spectrometer for Chemistry

有了这项来自主要研究仪器（MRI）计划的奖项，富兰克林和马歇尔学院的化学系将获得一台400 MHz核磁共振（NMR）光谱仪。该设备将使研究人员能够在锤头状核酶的研究中对作为过渡态类似物的atranyl核苷进行研究，在体内掺入光交联氨基酸以增加蛋白质稳定性，使用荧光化学传感器进行分子识别，[1，3]碳位移的机制，有机锗化合物中的超配位，以及铅复盐中的结构-晶格能量关系。 核磁共振（NMR）光谱是化学家用来阐明分子结构的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于从事前沿研究的化学家来说，使用最先进的NMR光谱仪是必不可少的。这些NMR研究的结果将对合成有机金属化学和生物化学产生影响。

With this award from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at Franklin and Marshall College will acquire a 400 MHz nuclear magnetic resonance (NMR) Spectrometer. This equipment will enable researchers to carry out studies on atranyl-nucleosides as transition state analogs in the study of the hammerhead ribozyme, in vivo incorporation of photocrosslinked amino acids to increase protein stability, molecular recognition using fluorescent chemsensors, the mechanism of the [1,3]carbon shift, hypercoordination in organogermanium compounds, and the structure-lattice energy relationship in lead double salts. Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in synthetic organometallic chemistry and biochemistry.