Acquisition of a 400 MHz Cyber-Enabled Nuclear Magnetic Resonance Spectrometer for Teaching and Research

采购 400 MHz 网络核磁共振波谱仪用于教学和研究

• 批准号: 0840451
• 负责人: Colin Nuckolls
• 金额: $ 59.94万
• 依托单位: Columbia University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-02-01 至 2012-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0840451&HistoricalAwards=false
• 关键词: Acquisition; 400; MHz; Cyber; Enabled

With support from the Chemistry Research Instrumentation and Facilities: Multiuser program (CRIF:MU), the Department of Chemistry at Columbia University will acquire a 400 MHz NMR spectrometer capable of measurements on solids and solutions. The spectrometer will improve the diverse research capabilities at Columbia which spans the range from applying synthetic chemistry methods to nano-science problems, to developing new solid-state NMR methods for studying proteins, to investigating binding and catalysis in aqueous solutions with enzyme mimics based on polymers. Nuclear Magnetic Resonance (NMR) spectroscopy is the most broadly used tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances and to provide information on the arrangement and connectivity of atoms in molecules. Dynamical information is obtained providing insight on the motions of molecules. This cyber-enabled NMR will provide a remote access interface that will enhance many Columbia programs that promote teaching and learning of undergraduates and high school teachers and students as well as assist research activities of users from other neighboring campuses. This cyber enabled remote access is projected to comprise about one third of the total instrument usage.

在化学研究仪器和设施：多用户计划（CRIF:MU）的支持下，哥伦比亚大学化学系将获得一台能够测量固体和溶液的400 MHz核磁共振光谱仪。光谱仪将提高哥伦比亚大学的各种研究能力，从应用合成化学方法到纳米科学问题，到开发用于研究蛋白质的新型固态核磁共振方法，再到研究基于聚合物的酶模拟物在水溶液中的结合和催化作用。核磁共振（NMR）波谱是化学家用于分子结构分析的最广泛使用的工具。它用于识别未知物质，并提供有关分子中原子的排列和连通性的信息。获得的动力学信息提供了对分子运动的深入了解。这个网络核磁共振将提供一个远程访问接口，将增强哥伦比亚大学的许多项目，促进本科生和高中教师和学生的教学和学习，并协助来自其他邻近校园的用户的研究活动。这种网络远程访问预计将占仪器总使用量的三分之一左右。