Mechanotransduction Networks in Arabidopsis
拟南芥中的力转导网络
基本信息
- 批准号:1557899
- 负责人:
- 金额:$ 61.31万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Continuing Grant
- 财政年份:2016
- 资助国家:美国
- 起止时间:2016-06-01 至 2021-05-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Plants respond to touch stimulation such as the wind, rain or the brushing by of animals by switching on a series of responses that make them sturdier and more resistant to damage. This research seeks to discover the genes that allow plants to trigger these responses. Results from this research will help define how plants defend themselves against environmental stresses with potential practical applications in the breeding or engineering of more resistant crops. The work will also involve the training of postdoctoral researchers, graduate students and undergraduate students in plant science. The program will help promote an understanding of plant research to the general public thorough a series of presentations and practical demonstrations.Despite its key role in determining their form and function, the molecular machinery underlying plant mechanical sensing and response remains very poorly defined. In addition, the mechanisms behind the known crosstalk between the mechanical and defense response systems remains largely uncharacterized. Changes in cytoplasmic Ca2+ are known to be some of the earliest signals generated by both mechanical stimuli and defense elicitors. This research program therefore seeks to define the role of the Ca2+-responsive calmodulin and calmodulin-like gene families in these processes. Bioinformatics will first be used to define the calmodulin and calmodulin-like protein-related mechanical response network. Analysis of gene expression, plant development, Ca2+ dynamics and pathogen sensitivity in mutants in these network genes will then be made to test their functional roles in touch and pathogen responses. These analyses will help to define the roles of these network elements in: (1) mechanical signaling and, (2) the crosstalk between mechanical and defense responses.
植物对触摸刺激,如风、雨或动物的擦身而过,做出一系列反应,使它们更坚固,更能抵抗伤害。这项研究旨在发现允许植物触发这些反应的基因。这项研究的结果将有助于确定植物如何抵御环境压力,并在育种或工程上具有潜在的实际应用。这项工作还将涉及培训博士后研究人员、研究生和植物科学本科生。该计划将通过一系列的演讲和实践演示,帮助促进公众对植物研究的理解。尽管它在决定它们的形式和功能方面发挥着关键作用,但植物机械传感和响应的分子机制仍然非常不清楚。此外,机械和防御反应系统之间的已知串扰背后的机制在很大程度上仍然没有特征。细胞质Ca 2+的变化是机械刺激和防御诱导子产生的最早信号。因此,本研究计划旨在确定在这些过程中的钙离子响应钙调素和钙调素样基因家族的作用。生物信息学将首先用于定义钙调素和钙调素样蛋白相关的机械响应网络。然后分析这些网络基因中突变体的基因表达、植物发育、Ca2+动态和病原体敏感性,以测试它们在触摸和病原体响应中的功能作用。这些分析将有助于定义这些网络元素在以下方面的作用:(1)机械信号,(2)机械和防御反应之间的串扰。
项目成果
期刊论文数量(10)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Using GCaMP3 to Study Ca2+ Signaling in Nicotiana Species
- DOI:10.1093/pcp/pcx053
- 发表时间:2017-07-01
- 期刊:
- 影响因子:4.9
- 作者:DeFalco, Thomas A.;Toyota, Masatsugu;Yoshioka, Keiko
- 通讯作者:Yoshioka, Keiko
Wide-Field, Real-Time Imaging of Local and Systemic Wound Signals in Arabidopsis
拟南芥局部和全身伤口信号的广域实时成像
- DOI:10.3791/62114
- 发表时间:2021
- 期刊:
- 影响因子:0
- 作者:Uemura, Takuya;Wang, Jiaqi;Aratani, Yuri;Gilroy, Simon;Toyota, Masatsugu
- 通讯作者:Toyota, Masatsugu
A low-cost and open-source platform for automated imaging
- DOI:10.1186/s13007-019-0392-1
- 发表时间:2019-01-28
- 期刊:
- 影响因子:5.1
- 作者:Lien, Max R.;Barker, Richard J.;Townsend, Philip A.
- 通讯作者:Townsend, Philip A.
The fast and the furious: rapid long-range signaling in plants
- DOI:10.1093/plphys/kiaa098
- 发表时间:2021-01-07
- 期刊:
- 影响因子:7.4
- 作者:Johns, Sarah;Hagihara, Takuma;Gilroy, Simon
- 通讯作者:Gilroy, Simon
Interplay of Plasma Membrane and Vacuolar Ion Channels, Together with BAK1, Elicits Rapid Cytosolic Calcium Elevations in Arabidopsis during Aphid Feeding
- DOI:10.1105/tpc.17.00136
- 发表时间:2017-06-01
- 期刊:
- 影响因子:11.6
- 作者:Vincent, Thomas R.;Avramova, Marieta;Sanders, Dale
- 通讯作者:Sanders, Dale
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Simon Gilroy其他文献
Root Hair Development
- DOI:
10.1007/s00344-003-0007-x - 发表时间:
2003-04-28 - 期刊:
- 影响因子:4.400
- 作者:
Tatiana Bibikova;Simon Gilroy - 通讯作者:
Simon Gilroy
A Comparison between Quin-2 and Aequorin as Indicators of Cytoplasmic Calcium Levels in Higher Plant Cell Protoplasts.
Quin-2 和水母发光蛋白作为高等植物细胞原生质体细胞质钙水平指标的比较。
- DOI:
10.1104/pp.90.2.482 - 发表时间:
1989 - 期刊:
- 影响因子:7.4
- 作者:
Simon Gilroy;W. A. Hughes;Anthony Trewavas - 通讯作者:
Anthony Trewavas
A touchy subject: Casup2+/sup signaling during leaf movements in Mimosa
一个敏感的话题:含羞草叶片运动过程中的 Casup2+/sup 信号传导
- DOI:
10.1016/j.ceca.2023.102695 - 发表时间:
2023-03-01 - 期刊:
- 影响因子:4.000
- 作者:
Arkadipta Bakshi;Sarah J. Swanson;Simon Gilroy - 通讯作者:
Simon Gilroy
Signal Transduction in Barley Aleurone Protoplasts Is Calcium Dependent and Independent.
大麦糊粉原生质体中的信号转导是钙依赖性和独立性的。
- DOI:
10.1105/tpc.8.12.2193 - 发表时间:
1996 - 期刊:
- 影响因子:0
- 作者:
Simon Gilroy - 通讯作者:
Simon Gilroy
Signal processing and transduction in plant cells: the end of the beginning?
植物细胞中的信号处理与转导:开端的终结?
- DOI:
10.1038/35067109 - 发表时间:
2001-04-01 - 期刊:
- 影响因子:90.200
- 作者:
Simon Gilroy;Anthony Trewavas - 通讯作者:
Anthony Trewavas
Simon Gilroy的其他文献
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{{ truncateString('Simon Gilroy', 18)}}的其他基金
Collaborative Research: Systemic Signailng Networks in Arabidopsis
合作研究:拟南芥系统信号网络
- 批准号:
2016177 - 财政年份:2020
- 资助金额:
$ 61.31万 - 项目类别:
Standard Grant
Ca2+ Waves in Systemic Signaling Networks in Plants
植物系统信号网络中的 Ca2 波
- 批准号:
1329723 - 财政年份:2013
- 资助金额:
$ 61.31万 - 项目类别:
Continuing Grant
Integration of Hypoxic Signaling Networks
缺氧信号网络的整合
- 批准号:
1121380 - 财政年份:2011
- 资助金额:
$ 61.31万 - 项目类别:
Continuing Grant
Cellular Mechanisms of Mechanotransduction in Arabidopsis
拟南芥机械力转导的细胞机制
- 批准号:
0641288 - 财政年份:2007
- 资助金额:
$ 61.31万 - 项目类别:
Standard Grant
Collaborative Research: Molecular, Biochemical and Signal Transduction Analysis of a Phytotoxic Root-Root Communication Process Mediated by (-)-Catechin in the Rhizosphere
合作研究:根际 (-)-儿茶素介导的植物毒性根-根通讯过程的分子、生化和信号转导分析
- 批准号:
0750968 - 财政年份:2007
- 资助金额:
$ 61.31万 - 项目类别:
Standard Grant
Collaborative Research: Molecular, Biochemical and Signal Transduction Analysis of a Phytotoxic Root-Root Communication Process Mediated by (-)-Catechin in the Rhizosphere
合作研究:根际 (-)-儿茶素介导的植物毒性根-根通讯过程的分子、生化和信号转导分析
- 批准号:
0336738 - 财政年份:2004
- 资助金额:
$ 61.31万 - 项目类别:
Standard Grant
Multiphoton Confocal Microscope for Plant Cell Biology
用于植物细胞生物学的多光子共焦显微镜
- 批准号:
0301460 - 财政年份:2003
- 资助金额:
$ 61.31万 - 项目类别:
Standard Grant
Signal Transduction in Root Gravitropism
根向地性中的信号转导
- 批准号:
0212099 - 财政年份:2002
- 资助金额:
$ 61.31万 - 项目类别:
Standard Grant
Signal Transduction in Root Gravitropism
根向地性中的信号转导
- 批准号:
9874445 - 财政年份:1999
- 资助金额:
$ 61.31万 - 项目类别:
Continuing Grant
Signal Transduction in Arabidopsis Root Gravitropism
拟南芥根向地性中的信号转导
- 批准号:
9513991 - 财政年份:1996
- 资助金额:
$ 61.31万 - 项目类别:
Standard Grant
相似国自然基金
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相似海外基金
Collaborative Research: Systemic Signailng Networks in Arabidopsis
合作研究:拟南芥系统信号网络
- 批准号:
2016177 - 财政年份:2020
- 资助金额:
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Standard Grant
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2016143 - 财政年份:2020
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Visualizing Gene Regulatory Networks in Arabidopsis thaliana for Understanding Network Biology
可视化拟南芥基因调控网络以了解网络生物学
- 批准号:
529003-2018 - 财政年份:2018
- 资助金额:
$ 61.31万 - 项目类别:
Alexander Graham Bell Canada Graduate Scholarships - Master's
EAPSI:Identifying Gene Networks that Control Root Hair Growth in Arabidopsis Thaliana
EAPSI:识别控制拟南芥根毛生长的基因网络
- 批准号:
1514779 - 财政年份:2015
- 资助金额:
$ 61.31万 - 项目类别:
Fellowship Award
Molecular networks underpinning root development in Arabidopsis and crops
支撑拟南芥和农作物根部发育的分子网络
- 批准号:
1644066 - 财政年份:2015
- 资助金额:
$ 61.31万 - 项目类别:
Studentship
Networks of Heterotrimeric G alpha Subunit Signaling to K+ Channels in Arabidopsis Guard Cells
拟南芥保卫细胞中 K 通道异三聚体 G α 亚基信号传导网络
- 批准号:
1121612 - 财政年份:2011
- 资助金额:
$ 61.31万 - 项目类别:
Continuing Grant
Collaborative Research: Arabidopsis 2010: Deciphering mRNP Networks
合作研究:拟南芥 2010:破译 mRNP 网络
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1021969 - 财政年份:2010
- 资助金额:
$ 61.31万 - 项目类别:
Continuing Grant
Arabidopsis 2010: Protein Interacting Networks and Site-Specific Phosphorylation in Leucine-Rich Repeat Receptor-Like Kinase Function
拟南芥 2010:富含亮氨酸的重复受体样激酶功能中的蛋白质相互作用网络和位点特异性磷酸化
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- 资助金额:
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Continuing Grant
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1022435 - 财政年份:2010
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