Electrochemically Driven Molybdoenzyme Catalysis

电化学驱动钼酶催化

• 批准号: DP0880288
• 负责人: Prof Paul Bernhardt
• 金额: $ 17.21万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0880288
• 关键词: Electrochemically; Driven; Molybdoenzyme; Catalysis

Enzymes that catalyse oxidation and reduction reactions need to exchange electrons with their substrate and this supply of electrons needs to be sustained. Artificially reconstituted systems can be developed where the enzyme is coupled with an electrode and the current (electrons) exchanged during the reaction are measured directly. In this project we will reveal whether some unusual and unexplained electrochemical phenomena seen before are related to the properties of the enzymes themselves or the ways in which their experiments have been conducted.

催化氧化和还原反应的酶需要与其底物交换电子，并且这种电子供应需要持续。可以开发酶促重构系统，其中酶与电极偶联，并且直接测量反应期间交换的电流（电子）。在这个项目中，我们将揭示以前看到的一些不寻常和无法解释的电化学现象是否与酶本身的性质或其实验进行的方式有关。