Pioneering stable copper carbanions for new C-C bond forming paradigms

开创性稳定的铜碳负离子，用于新的 C-C 键形成范例

• 批准号: DP210102150
• 负责人: Prof Paul Bernhardt
• 金额: $ 27.43万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-02-08 至 2024-02-07
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP210102150
• 关键词: Pioneering; stable; copper; carbanions; new

The stabilisation of highly reactive carbanions underpins advances in chemical synthesis of new compounds including polymers, agrichemicals and pharmaceuticals. This project aims to deliver an innovative chemical reactivity platform, underpinned by copper carbanion complexes accessed via synthetic electrochemistry. Carbanions are essential components of carbon-carbon bond forming reactions but their high reactivity can be problematic. Expected outcomes of this project are an understanding of why these novel copper compounds are stable and how they can be utilised as synthetic reagents. This should provide significant benefits in unlocking the synthetic potential of a new class of chemical compound that has until now remained unexplored.

高活性碳负离子的稳定化支持了新化合物（包括聚合物、农用化学品和药物）的化学合成的进展。该项目旨在提供一个创新的化学反应平台，以通过合成电化学获得的铜碳负离子络合物为基础。碳负离子是碳-碳键形成反应的基本组分，但它们的高反应性可能是有问题的。该项目的预期成果是了解为什么这些新型铜化合物是稳定的，以及如何将它们用作合成试剂。这将为释放迄今为止尚未探索的一类新化合物的合成潜力提供重大益处。