Pioneering stable copper carbanions for new C-C bond forming paradigms

开创性稳定的铜碳负离子，用于新的 C-C 键形成范例

• 批准号: DP210102150
• 负责人: Prof Paul Bernhardt
• 金额: $ 27.43万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-02-08 至 2024-02-07
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP210102150
• 关键词: Pioneering; stable; copper; carbanions; new

The stabilisation of highly reactive carbanions underpins advances in chemical synthesis of new compounds including polymers, agrichemicals and pharmaceuticals. This project aims to deliver an innovative chemical reactivity platform, underpinned by copper carbanion complexes accessed via synthetic electrochemistry. Carbanions are essential components of carbon-carbon bond forming reactions but their high reactivity can be problematic. Expected outcomes of this project are an understanding of why these novel copper compounds are stable and how they can be utilised as synthetic reagents. This should provide significant benefits in unlocking the synthetic potential of a new class of chemical compound that has until now remained unexplored.

高反应性碳纤维的稳定构成了包括聚合物，农业化学物质和药物在内的新化合物化学合成的进步。该项目旨在提供一个创新的化学反应平台，这是由通过合成电化学访问的铜碳纤维综合体为基础提供的。 Carbanions是碳碳键反应的重要组成部分，但它们的高反应性可能是有问题的。该项目的预期结果是对这些新型铜化合物为何稳定以及如何用作合成试剂的理解。这应该在解锁迄今为止尚未探索的新型化合物的合成潜力方面具有重大好处。