MRI: Acquisition of a 500 MHz Nuclear Magnetic Resonance (NMR) Spectrometer

该奖项由主要研究仪器项目和化学研究仪器项目支持。加州大学圣巴巴拉分校(UCSB)的张黎明教授及其同事布鲁斯·利普舒茨、特雷弗·海顿和哈维尔·里德·德·阿拉尼斯获得了一台500 MHz核磁共振波谱仪，配备了一个液氮冷却探头和一个具有多核能力的探头。这种光谱仪允许在各种领域进行研究，例如那些加速具有重大经济意义的化学反应的领域，以及那些促进生物相关物种研究的领域。总的来说，核磁共振波谱是化学家用来描述分子结构的最强大的工具之一。核磁共振被用来识别未知物质，表征分子中原子的特定排列，并研究分子在溶液或固体中相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱仪是必不可少的。相对于标准的核磁共振探头，低温探头的灵敏度显著提高，而多核探头则允许研究常见氢原子和碳原子以外的多种元素。核磁共振研究提高了对合成有机/无机化学、材料化学和生物化学的理解。该仪器是教学和研究不可分割的一部分。这种可广泛使用的仪器设备加强了区域仪器基础设施，并帮助推进了18个研究小组中约200名普通本科生和研究生研究人员、博士后和访问学者的科学生涯。该光谱仪丰富了美国国家科学基金会资助的几个科学、技术、工程和数学(STEM)项目中未被充分代表的本科生的教育和培训经验，以及UCSB和圣巴巴拉社区学院化学和生物化学实验室课程的数百名本科生的教育和培训经验。这种核磁共振仪器还促进了当地几家专门从事清洁能源和食品保存的初创公司的研发(R&A；D)工作。授予核磁共振光谱仪和低温探头旨在加强各级的研究和教育。这一成果尤其有利于发展纳米团簇形成的热化学模型，并有助于对鳗系元素电子结构的探索。该仪器还为研究含氟功能聚合物和那些在硼催化的肽键形成中使用硼-11同位素的研究人员提供服务。最后，光谱仪有利于复杂生物活性天然产物的合成和表征。这一奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

This award is supported by the Major Research Instrumentation and the Chemistry Research Instrumentation Programs. Professor Liming Zhang from the University of California Santa Barbara (UCSB) and colleagues Bruce Lipshutz, Trevor Hayton and Javier Read de Alaniz have acquired a 500 MHz NMR spectrometer equipped with a liquid-nitrogen cooled probe and a probe with multinuclear capabilities. This spectrometer allows research in a variety of fields such as those that accelerate chemical reactions of significant economic importance, as well as those that facilitate studies of biologically relevant species. In general, Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists to describe the structure of molecules. NMR is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The cryogenic probe provides a significant increase in sensitivity relative to standard NMR probes while the multinuclear probe allows study of a wide range of elements above and beyond the common hydrogen and carbon atoms. The NMR studies improve understanding of synthetic organic/inorganic chemistry, materials chemistry and biochemistry. This instrument is an integral part of teaching as well as research. This broadly accessible instrumentation strengthens the regional instrumentation infrastructure and helps advance the scientific careers of about 200 regular undergraduate and graduate researchers, postdocs and visiting scholars in more than 18 research groups. The spectrometer enriches the education and training experience of underrepresented undergraduate students in several NSF-supported science, technology, engineering and mathematics (STEM) programs and several hundred undergraduate students in chemistry and biochemistry laboratory classes at UCSB and from Santa Barbara Community College. This NMR instrumentation also facilitates research and development (R&D) efforts of several local startup companies specializing in clean energy and food preservation.The award of the NMR spectrometer with a cryoprobe is aimed at enhancing research and education at all levels. This acquisition especially benefits the development of a thermochemical model for nanocluster formation and the exploration of actinide electronic structures. The instrumentation also serves researchers studying fluorinated functional polymers and those using boron-11 isotopes in boron-catalyzed peptide bond formation. Finally, the spectrometer benefits the syntheses and characterization of complex bioactive natural products.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.