Neuroendocrinological Studies of Fish Puberty

kisspeptins是由kissgenes编码的一种蛋白质，在脊椎动物中起着重要的生殖调节作用.在本研究中，我们评估的效力Kiss 1和Kiss 2诱导青春期开始在青春期前的鲭鱼。与其他处理相比，Kiss 1处理的鱼的性腺指数（GSI）显着增加。在组织学上，66.7%的Kiss 1处理的鱼表现出精子在睾丸中的存在。然而，Kiss 2 -12处理的鱼仅显示精母细胞作为睾丸中的高级生殖细胞。相比之下，在初始和未处理的最终对照鱼的睾丸中仅观察到精原细胞。性类固醇的水平显着较高的Kiss 1处理的鱼。这些结果表明Kiss 1肽用于加速鲭鱼青春期的开始。

Kisspeptins, encoded by kissgenes have emerged as critical regulator of reproductive function in vertebrates. In the present study, we evaluated the potency of Kiss1 and Kiss2 to induce pubertal onset in prepubertal chub mackerel. Gonadosomatic index (GSI) of Kiss1 treated fish increased significantly in comparison to other treatments. Histologically, 66.7% of Kiss1 treated fish exhibited presence of spermatozoa in the testes. However,Kiss2-12 treated fish showed only spermatocytes as the advanced germ cells in the testes. In contrast, only spermatogonia were observed in the testes of initial and untreated final control fish. Levels of sex steroids were significantly higher in Kiss1 treated fish. These results indicate application of Kiss1 peptides for accelerating pubertal onset in chub mackerel.