Neuroendocrinological Studies of Fish Puberty

由kissgenes编码的kisspeptin已成为脊椎动物生殖功能的关键调节因子。在本研究中，我们评估了Kiss1和Kiss2在青春期前鲐鱼中诱导青春期发生的效力。与其他处理相比，Kiss1处理鱼的促性腺指数（GSI）显著升高。组织学上，66.7%的Kiss1处理鱼睾丸中存在精子。然而，Kiss2-12处理的鱼在睾丸中显示只有精母细胞是高级生殖细胞。相比之下，在初始对照鱼和未处理的最终对照鱼的睾丸中只观察到精原细胞。在Kiss1处理过的鱼中，性类固醇的水平明显更高。这些结果表明Kiss1肽在加速鲐鱼青春期发育中的应用。

Kisspeptins, encoded by kissgenes have emerged as critical regulator of reproductive function in vertebrates. In the present study, we evaluated the potency of Kiss1 and Kiss2 to induce pubertal onset in prepubertal chub mackerel. Gonadosomatic index (GSI) of Kiss1 treated fish increased significantly in comparison to other treatments. Histologically, 66.7% of Kiss1 treated fish exhibited presence of spermatozoa in the testes. However,Kiss2-12 treated fish showed only spermatocytes as the advanced germ cells in the testes. In contrast, only spermatogonia were observed in the testes of initial and untreated final control fish. Levels of sex steroids were significantly higher in Kiss1 treated fish. These results indicate application of Kiss1 peptides for accelerating pubertal onset in chub mackerel.