Application of FALI with antibody-like scaffolds to the high-throughput functional proteomic screen for therapeutic targets
Application of FALI with antibody-like scaffolds to the high-throughput functional proteomic screen for therapeutic targets
批准号:
26670127
负责人:
SAKURAI Takashi
金额:
$2.33万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2014
资助国家:
日本
项目状态:
已结题
起止时间:
2014-04-01 至 2016-03-31
中文摘要
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組換え抗体ライブラリーと光による蛋白質機能不活性化法(FALI)を用いた創薬標的探索
使用重组抗体库和光诱导蛋白功能失活 (FALI) 进行药物发现靶标搜索
DOI:
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发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
DOI:
10.1016/j.jbiotec.2015.08.020
发表时间:
2015-10-20
期刊:
JOURNAL OF BIOTECHNOLOGY
影响因子:
4.1
作者:
[Mochizuki, Yuki, Suzuki, Takeru, Nemoto, Naoto]
通讯作者:
Nemoto, Naoto
試験管内選択により取得されたジスルフィドリッチペプチドアプタマーは分子認識スキャフォールドとなりうるか?
体外筛选获得的富含二硫键的肽适配体能否作为分子识别支架?
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[望月 佑樹, 根本 直人]
通讯作者:
根本 直人
人工合成ラクダ科単ドメイン抗体(VHH)ライブラリを用いたsurvivin結合分子のcDNA display法による試験管内淘汰
使用人工合成的骆驼单域抗体 (VHH) 文库,通过 cDNA 展示方法体外选择存活蛋白结合分子
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[木村 真之介, 望月 佑樹, 鈴木 武尊, 根本 直人]
通讯作者:
根本 直人
Studies on solar activity and its influence on Earth's environment using data over a century
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批准号:20K04033
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.75万
-
财政年份:2020
-
负责人:SAKURAI Takashi
-
依托单位:
Use of FALI with cDNA display single-domain antibodies for efficient functional screening of therapeutic targets
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批准号:16K15206
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项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.33万
-
财政年份:2016
-
负责人:SAKURAI Takashi
-
依托单位:
Microdomain-dependent acceleration mechanisms for amyloidogenic processing of amyloid precursor protein induced by endocytic membrane traffic impairment
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批准号:23300128
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.65万
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财政年份:2011
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负责人:SAKURAI Takashi
-
依托单位:
Application of a cell-free protein display technology to the high-throughput functional proteomic screen for regulators of neuron-glia interaction
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批准号:23659141
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
-
财政年份:2011
-
负责人:SAKURAI Takashi
-
依托单位:
Development of a Pulse Detonation Combustor for a Several kW-class Micro Gas Turbine
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批准号:21760653
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.16万
-
财政年份:2009
-
负责人:SAKURAI Takashi
-
依托单位:
Insulin secretion in pancreaticβcells and control of blood glucose level studied by fiber-coupled micro endoscopy
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批准号:21590231
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.75万
-
财政年份:2009
-
负责人:SAKURAI Takashi
-
依托单位:
A novel microdomain-dependent regulatory mechanism of amyloid precursor protein processing
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批准号:20300125
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$12.06万
-
财政年份:2008
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负责人:SAKURAI Takashi
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依托单位:
Development of effective conservative combined therapy for malignant tumor using quantitative analysis for vascular structure
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批准号:19592187
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
-
财政年份:2007
-
负责人:SAKURAI Takashi
-
依托单位:
A new method for detecting lactate threshold by respiratory rate
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批准号:19700486
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.22万
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财政年份:2007
-
负责人:SAKURAI Takashi
-
依托单位:
Study on cholesterol-dependent regulatory mechanisms of amyloid precursor protein processing in membrane microdomains
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批准号:18500283
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.63万
-
财政年份:2006
-
负责人:SAKURAI Takashi
-
依托单位:
Preventative effects of exercise on the cardiovascular disease, ADL and cognitive function of the elderly with metabolic syndrome
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批准号:17500473
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.41万
-
财政年份:2005
-
负责人:SAKURAI Takashi
-
依托单位:
Studies on the Process of Magnetic Energy Build-up in Solar Flares by Using an Infrared Detector
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批准号:17204014
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$30.95万
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财政年份:2005
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负责人:SAKURAI Takashi
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依托单位:
Study on cholesterol-dependent regulatory mechanisms of amyloid precursor protein processing in lipid microdomains
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批准号:16500232
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.05万
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财政年份:2004
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负责人:SAKURAI Takashi
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依托单位:
Magnetic Field Evolution and Solar Flares
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批准号:08044104
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$1.54万
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财政年份:1996
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负责人:SAKURAI Takashi
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依托单位:
Observations of Solar Eclipse in South America on Nov.3,1994
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批准号:05041071
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$3.2万
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财政年份:1993
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负责人:SAKURAI Takashi
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依托单位:
Observational Studies of Magnetic Energy Storage and Release in Solar Flares
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批准号:63065001
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项目类别:Grant-in-Aid for Specially Promoted Research
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资助金额:$138.18万
-
财政年份:1988
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负责人:SAKURAI Takashi
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依托单位:
海外基金