Sociomedical-informative study on establishment of supporting model of health behavior changes

从出生到现在，个人在整个生活方式中所暴露的总环境一直在构成个人和社区的生活方式，或日常生活方式。众所周知，这种生活方式决定了患癌症、循环系统疾病和其他慢性病的风险。为了建立新的环境医学疾病预防和健康促进的理论和实践方案，我们对生活方式与综合健康潜力的相关性进行了定量研究。健康潜力通过一般体检资料的Ridit分析和多相分析以及淋巴细胞染色体变化、自然杀伤细胞活性和血清IgE水平等典型生物标志物的测量来评估；总体健康状况的评估通过多相健康检查的血生化、血压和尿液检测异常发生率的Ridit分析来评估。一般健康随着年龄的增长而下降，但随着生活方式的不同而变化很大。例如，生活方式差的人在20年代S的平均躯体健康水平与生活方式好的人在40年代的S大致相同。根据工人的随访结果，不健康的工人患心脏病、肝病、糖尿病等慢性病的风险显著增加。

The total environments to which individuals have been exposed throughout the lifestages from birth to the present time have been composing the individual and community lifestyles, or ways of daily living. Such lifestyles are known to determine the risks for development of cancers, circulatory diseases, and other chronic diseases. To establish new theory and practice programs for disease prevention and health promotion in the environmental medicine, we have quantitatively investigated correlations of lifestyle to comprehensive health potentials. The health potentials were assessed by both the ridit and multiphasic analysis of general health-check-up data, and the measurements of typical biomarkers such as lymphocyte chromosome alterations, natural-killer cell activities, and serum IgE levels.The general health status was assessed by the ridit analysis of the incidence of abnormal values in blood-biochemistry, blood-pressure, and urine tests of multiphasic health check-ups. The general health was found to decrease with aging, but to vary a lot according to their lifestyles. For example, the mean level of somatic health of the persons having poor lifestyles in the 20's was about the same that of those with good lifestyles in the 40's. According to the results of follow-up of workers, the unhealthy workers were found to have had significantly higher risks for the developments of chronic diseases such as heart attack, liver disease, and diabetes.