Regulatory Mechanisms of the Balance between Inflammation andAnti-inflammation by Cutokines
Regulatory Mechanisms of the Balance between Inflammation andAnti-inflammation by Cutokines
批准号:
22249009
负责人:
YOSHIMURA Akihiko
金额:
$31.2万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
细胞因子在调节先天免疫和适应性免疫中起重要作用。转化生长因子-E(transforminggrowthfactor-E,TGF-E)在T细胞稳态、Th 17和Treg分化、免疫抑制等方面发挥重要作用。在这项研究中,我们恶魔
英文摘要
Cytokines play essential roles in regulation of innate and adaptive immunity. The transforming growthfactor-E (TGF-E) has been shown to play pivotal roles in T-cell homeostasis, Th17 and Tregdifferentiation, and immune suppression. In this study, we demon
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Suppression of intestinalinflammation by PGE2, IL-10 and SOCS1
PGE2、IL-10 和 SOCS1 抑制肠道炎症
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Miura D., Fujimura Y., Yamato M., et al, 花岡文雄, Akihiko Yoshimura]
通讯作者:
Akihiko Yoshimura
Role of TGF-口eta-Smad2/3 signaling in helper Tcell function and differentiation
TGF-eta-Smad2/3 信号在辅助 T 细胞功能和分化中的作用
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Akihiko Yoshimura, Kenji Ichiyama]
通讯作者:
Kenji Ichiyama
DOI:
10.1128/mcb.05020-11
发表时间:
2011-09-01
期刊:
MOLECULAR AND CELLULAR BIOLOGY
影响因子:
5.3
作者:
[Joshi, Sneha, Pantalena, Luiz-Carlos, Youssef, Sawsan]
通讯作者:
Youssef, Sawsan
The IL-23-IL-17 axis inthe brain inflammation after stroke
IL-23-IL-17轴在中风后脑部炎症中的作用
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Kinoshita Y., Yamada K., Yamasaki T., et al, Akihiko Yoshimura]
通讯作者:
Akihiko Yoshimura
protein-2 modulates fas-mediated T cell apoptosisby interacting with caspase-8
Protein-2 通过与 Caspase-8 相互作用调节 fas 介导的 T 细胞凋亡
DOI:
--
发表时间:
2012
期刊:
J Immunol
影响因子:
4.4
作者:
[Sekine Y, Yamamoto C, Kakisaka M, MuromotoR, Kon S, Ashitomi D, Fujita N, Yoshimura A,Oritani K, Matsuda T. Signal-transducing adap]
通讯作者:
Matsuda T. Signal-transducing adap
共 33 条
Immune systems involved in the resolution of inflammation and tissue repair
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批准号:17H06175
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项目类别:Grant-in-Aid for Scientific Research (S)
-
资助金额:$131.71万
-
财政年份:2017
-
负责人:YOSHIMURA Akihiko
-
依托单位:
Identification of Cellular Signaling Mechanism that regulates inflammation and tissue repairing
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批准号:25221305
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项目类别:Grant-in-Aid for Scientific Research (S)
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资助金额:$122.8万
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财政年份:2013
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负责人:YOSHIMURA Akihiko
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依托单位:
Systemic Biology of T cell differentiation
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批准号:25670234
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.5万
-
财政年份:2013
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负责人:YOSHIMURA Akihiko
-
依托单位:
Systembiology of T-cell differentiation
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批准号:23659242
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.33万
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财政年份:2011
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负责人:YOSHIMURA Akihiko
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依托单位:
Molecular Mechanism of Regulation of the Cytokine Signal and Immunity
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批准号:18109005
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项目类别:Grant-in-Aid for Scientific Research (S)
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资助金额:$68.64万
-
财政年份:2006
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负责人:YOSHIMURA Akihiko
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依托单位:
Abnormal differentiation of tumor cells and tyrosine kinase regulation
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批准号:17014069
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$38.34万
-
财政年份:2005
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负责人:YOSHIMURA Akihiko
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依托单位:
Mechanism of Regulation of Tyrosine Kinase Signaling
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批准号:12219216
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$109.76万
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财政年份:2000
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负责人:YOSHIMURA Akihiko
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依托单位:
Screening of signal transducing molecules by using transient expression
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批准号:10557038
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.87万
-
财政年份:1998
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负责人:YOSHIMURA Akihiko
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依托单位:
Growth and differentiation signals of the erythropoietin receptor
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批准号:09470036
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.58万
-
财政年份:1997
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负责人:YOSHIMURA Akihiko
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依托单位:
Physiological Function and Signal Transduction Mechanism of the STAT5-target genes
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批准号:09044349
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$5.06万
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财政年份:1997
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负责人:YOSHIMURA Akihiko
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依托单位:
Growth and Differentiation through the Cytokine Receptors
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批准号:07044284
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$1.41万
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财政年份:1995
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负责人:YOSHIMURA Akihiko
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依托单位:
Structure and Signal Transduction of the Erythropoietin Receptor
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批准号:05680618
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.47万
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财政年份:1993
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负责人:YOSHIMURA Akihiko
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依托单位:
海外基金