Molecular mechanisms of chromatin formation and dynamics
Molecular mechanisms of chromatin formation and dynamics
批准号:
16084202
负责人:
KIMURA Hiroshi
金额:
$83.2万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research on Priority Areas
财政年份:
2004
资助国家:
日本
项目状态:
已结题
起止时间:
2004 至 2008
中文摘要
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英文摘要
本研究は、細胞核内のクロマチンダイナミクスの意義と制御機構を明らかにすることを目的として行われた。膜透過化細胞やアフリカツメガエル卵抽出液を用いた再構成系を用いて、ヒストンの交換やアセンブリに働く因子の同定と解析を行い、ゲノムの恒常性維持や複製における各ヒストンシャペロンの機能を明らかにした。また、生きた細胞におけるヒストン修飾のダイナミクスの解析法を確立した。
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Dynamics of histone modifications in living cells
活细胞中组蛋白修饰的动力学
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Yoneda, Y., Khanh Huy Bui, J. Yajima, 真行寺 千佳子, Hiroshi Kimura]
通讯作者:
Hiroshi Kimura
転写の活性化に伴うヒストン修飾のダイナミクス
与转录激活相关的组蛋白修饰动态
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Chen, Q., 木村宏]
通讯作者:
木村宏
Alterations of lysine modifications on histone H3 N-tail under drought stress conditions in Arabidopsis thaliana.
拟南芥干旱胁迫条件下组蛋白 H3 N 尾赖氨酸修饰的变化。
DOI:
--
发表时间:
2008
期刊:
Plant Cell Physiol. 49
影响因子:
--
作者:
[Kim, J.-M., Kim To, T., Ishida, J., Morosawa, T., Kawashima, M., Matsui, A., Toyoda, T., Kimura, H., Shinozaki, K. and Seki, M.]
通讯作者:
M.
光退色と光刺激による細胞内分子動態の解析
通过光漂白和光刺激分析细胞内分子动力学
DOI:
--
发表时间:
2007
期刊:
化学と生物 45
影响因子:
--
作者:
[有川安信, 中井光男, 渡利威士, 細田裕計, 猿倉信彦, 古川裕介, 白神宏之, 疇地宏, Satouh Y, 木村宏]
通讯作者:
木村宏
Inhibitors of the proteasome suppress homologous DNA recomvination in mammalian cells
蛋白酶体抑制剂抑制哺乳动物细胞中的同源 DNA 重组
DOI:
--
发表时间:
2007
期刊:
Cancer Research 67
影响因子:
--
作者:
[Murakawa, Y.]
通讯作者:
Y.
共 77 条
Cell therapy against intractable EB virus infection using immunological tolerance
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批准号:24659493
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
-
财政年份:2012
-
负责人:KIMURA Hiroshi
-
依托单位:
An on-chip hepatic metabolism model for pharmacokinetic studies
-
批准号:24710141
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.91万
-
财政年份:2012
-
负责人:KIMURA Hiroshi
-
依托单位:
The decreases in hypoxic ventilatory response affect acute exacerbation in patients with respiratory failure and/or obesity hypoventilation syndrome
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批准号:23591158
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.24万
-
财政年份:2011
-
负责人:KIMURA Hiroshi
-
依托单位:
Live cell imaging of histone methylation and inactive X chromosome dynamics
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批准号:22370063
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.9万
-
财政年份:2010
-
负责人:KIMURA Hiroshi
-
依托单位:
Integrated "Body on a Chip" system for cell-based assay
-
批准号:22710120
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.58万
-
财政年份:2010
-
负责人:KIMURA Hiroshi
-
依托单位:
Science and Technology Studies to Develop the Governance for Effective Use of Nuclear Energy
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批准号:21360464
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.9万
-
财政年份:2009
-
负责人:KIMURA Hiroshi
-
依托单位:
Diagnosis and pathogenetic analysis using a novel identification method for EBV-infected cells
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批准号:21591384
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.83万
-
财政年份:2009
-
负责人:KIMURA Hiroshi
-
依托单位:
Basic Researches to reexamine Problem Group called the Absolute and a Place, from the Perspective of an Image and a Field
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批准号:21520040
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.08万
-
财政年份:2009
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负责人:KIMURA Hiroshi
-
依托单位:
Infrared Spectra of Comets as a Barometer for Their Evolution
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批准号:21340040
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.81万
-
财政年份:2009
-
负责人:KIMURA Hiroshi
-
依托单位:
Relative dielectric constant measurement system for natural soil in microwave region
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批准号:20560393
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2008
-
负责人:KIMURA Hiroshi
-
依托单位:
Functional morphologic study of the peripheral cholinergic nervous system in human.
-
批准号:20390051
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$7.4万
-
财政年份:2008
-
负责人:KIMURA Hiroshi
-
依托单位:
The structure and dynamics of chromatin harboring specific histone modifications
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批准号:19370076
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.65万
-
财政年份:2007
-
负责人:KIMURA Hiroshi
-
依托单位:
Integration of legged locomotion control methods and understanding of motion intelligence from the view points of both mechanics and control
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批准号:19500166
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.75万
-
财政年份:2007
-
负责人:KIMURA Hiroshi
-
依托单位:
Hypoxic stress in sleep apnea causes systemic inflammation and promotes atherosclerosis.
-
批准号:19390226
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.65万
-
财政年份:2007
-
负责人:KIMURA Hiroshi
-
依托单位:
Biosyntehsis and Properties of Copolyesters with 4-Hydroxyalkanoic Acid Unit
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批准号:16550133
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.05万
-
财政年份:2004
-
负责人:KIMURA Hiroshi
-
依托单位:
Research on the generation mechanism of the behavior intelligence for a quadruped robot assisting the disabilities
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批准号:15500104
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.73万
-
财政年份:2003
-
负责人:KIMURA Hiroshi
-
依托单位:
Hypoxic stress and atherosclerosis in patients with sleep apnea-hypopnea syndrome
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批准号:15590821
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.18万
-
财政年份:2003
-
负责人:KIMURA Hiroshi
-
依托单位:
Regulation of gene expression and chromatin dynamics in living cells
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批准号:15370073
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.92万
-
财政年份:2003
-
负责人:KIMURA Hiroshi
-
依托单位:
Pathogenesis on reactivation of viral infections in immunocompromised hosts and its prophylaxis and therapy.
-
批准号:13670793
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.66万
-
财政年份:2001
-
负责人:KIMURA Hiroshi
-
依托单位:
Assessment using hydra of endocrine disruptors contaminated in freshwater environment
-
批准号:13680623
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.98万
-
财政年份:2001
-
负责人:KIMURA Hiroshi
-
依托单位:
海外基金