Functional morphologic study of the peripheral cholinergic nervous system in human.
Functional morphologic study of the peripheral cholinergic nervous system in human.
批准号:
20390051
负责人:
KIMURA Hiroshi
金额:
$7.4万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
We have previously demonstrated that the neurotransmitter acetylcholine is synthesized by two enzymes, cChAT and pChAT. The pChAT occurs not only in peripheral cholinergic neurons but also in neuronal crest derived neurons (primary sensory, postganglionic sympathetic and intramural enteric neurons) of experimental animals. The present study aims at examining whether pChAT is also present in humans. Using protein purification and antibody production methods, we have firstly succeeded to visualize neurons containing human pChAT.
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DOI:
10.1002/cne.21761
发表时间:
2008-08-20
期刊:
JOURNAL OF COMPARATIVE NEUROLOGY
影响因子:
2.5
作者:
[D'Este, Loredana, Kimura, Shin, Renda, Tindaro G.]
通讯作者:
Renda, Tindaro G.
Peripheral type of choline acetyltransferase : Biological and evolutionary implications for novel mechanisms in cholinergic system.(2011).
胆碱乙酰转移酶的外周型:胆碱能系统新机制的生物学和进化意义。(2011)。
DOI:
--
发表时间:
2011
期刊:
J Chem Neuroanat.
影响因子:
--
作者:
[Bellier JP, Kimura H.]
通讯作者:
Kimura H.
Recent advances in cholinergic mechanisms with special reference to the identification of choline acetyltransferase of the peripheral type (pChAT)
胆碱能机制的最新进展,特别是外周型胆碱乙酰转移酶(pChAT)的鉴定
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[磯貝純夫, 木村英二, 人見次郎, 木村宏]
通讯作者:
木村宏
コリン神経研究の最近の進歩 : 末梢型アセチルコリン合成酵素の同定
胆碱能神经学研究的最新进展:外周乙酰胆碱合酶的鉴定
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[磯貝純夫, 木村英二, 人見次郎, 木村宏]
通讯作者:
木村宏
DOI:
10.1111/j.1749-6632.2010.05436.x
发表时间:
2010-01-01
期刊:
NEURONS AND NETWORKS IN THE SPINAL CORD
影响因子:
--
作者:
[Hochman, Shawn, Shreckengost, Jacob, Quevedo, Jorge]
通讯作者:
Quevedo, Jorge
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Infrared Spectra of Comets as a Barometer for Their Evolution
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The structure and dynamics of chromatin harboring specific histone modifications
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Molecular mechanisms of chromatin formation and dynamics
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Regulation of gene expression and chromatin dynamics in living cells
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Hypoxic stress and atherosclerosis in patients with sleep apnea-hypopnea syndrome
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Pathogenesis on reactivation of viral infections in immunocompromised hosts and its prophylaxis and therapy.
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