Integrated "Body on a Chip" system for cell-based assay
Integrated "Body on a Chip" system for cell-based assay
批准号:
22710120
负责人:
KIMURA Hiroshi
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
在这个项目中,我们提出并开发了一个芯片上的吸收和代谢模型,作为动物实验的替代方法。我们在该装置中用混合的小肠、肝脏和肺模型细胞进行了抗癌药物测试,并显示了评估药代动力学的可能性。
英文摘要
In this project, we proposed and developed an on-chip absorption and metabolism model as an alternative method of animal tests. We performed anti-cancer drug tests with coclutured small intestine, liver and lung model cells in the device and showed a possibility of evaluation of pharmacokinetics.
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Microfluidic Spatial Control for Cell-based Assay
用于细胞检测的微流体空间控制
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[H. Kimura, T. Fujii]
通讯作者:
T. Fujii
マイクロ流体技術によるバイオ操作~医療応用へ向けて~
使用微流体技术进行生物操纵 - 迈向医疗应用 -
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[木村啓志, 藤井輝夫]
通讯作者:
藤井輝夫
Bile canaliculi formation by aligning rat primary hepatocyte in a micro fluidic device
通过在微流体装置中排列大鼠原代肝细胞来形成胆小管
DOI:
--
发表时间:
2011
期刊:
Biomicrofluidics
影响因子:
3.2
作者:
[Y. Nakao, H. Kimura, Y. Sakai, T. Fujii]
通讯作者:
T. Fujii
Application of Cell-free Expression of GFP for Evaluation of Microsystems
GFP 无细胞表达在微系统评估中的应用
DOI:
10.2741/4029
发表时间:
2012
期刊:
Frontiers in Bioscience
影响因子:
--
作者:
[T.Nojima, S.Kaneda, H.Kimura, T.Yamamoto, T.Fujii]
通讯作者:
T.Fujii
マイクロ流体デバイスを応用した微小環境操作
使用微流体装置操纵微环境
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[木村啓志, 藤井輝夫]
通讯作者:
藤井輝夫
共 8 条
Cell therapy against intractable EB virus infection using immunological tolerance
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批准号:24659493
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
-
财政年份:2012
-
负责人:KIMURA Hiroshi
-
依托单位:
An on-chip hepatic metabolism model for pharmacokinetic studies
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批准号:24710141
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.91万
-
财政年份:2012
-
负责人:KIMURA Hiroshi
-
依托单位:
The decreases in hypoxic ventilatory response affect acute exacerbation in patients with respiratory failure and/or obesity hypoventilation syndrome
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批准号:23591158
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.24万
-
财政年份:2011
-
负责人:KIMURA Hiroshi
-
依托单位:
Live cell imaging of histone methylation and inactive X chromosome dynamics
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批准号:22370063
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.9万
-
财政年份:2010
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负责人:KIMURA Hiroshi
-
依托单位:
Science and Technology Studies to Develop the Governance for Effective Use of Nuclear Energy
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批准号:21360464
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.9万
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财政年份:2009
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负责人:KIMURA Hiroshi
-
依托单位:
Diagnosis and pathogenetic analysis using a novel identification method for EBV-infected cells
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批准号:21591384
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
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财政年份:2009
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负责人:KIMURA Hiroshi
-
依托单位:
Infrared Spectra of Comets as a Barometer for Their Evolution
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批准号:21340040
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.81万
-
财政年份:2009
-
负责人:KIMURA Hiroshi
-
依托单位:
Basic Researches to reexamine Problem Group called the Absolute and a Place, from the Perspective of an Image and a Field
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批准号:21520040
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.08万
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财政年份:2009
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负责人:KIMURA Hiroshi
-
依托单位:
Relative dielectric constant measurement system for natural soil in microwave region
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批准号:20560393
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
-
财政年份:2008
-
负责人:KIMURA Hiroshi
-
依托单位:
Functional morphologic study of the peripheral cholinergic nervous system in human.
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批准号:20390051
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.4万
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财政年份:2008
-
负责人:KIMURA Hiroshi
-
依托单位:
The structure and dynamics of chromatin harboring specific histone modifications
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批准号:19370076
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.65万
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财政年份:2007
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负责人:KIMURA Hiroshi
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依托单位:
Integration of legged locomotion control methods and understanding of motion intelligence from the view points of both mechanics and control
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批准号:19500166
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.75万
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财政年份:2007
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负责人:KIMURA Hiroshi
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依托单位:
Hypoxic stress in sleep apnea causes systemic inflammation and promotes atherosclerosis.
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批准号:19390226
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.65万
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财政年份:2007
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负责人:KIMURA Hiroshi
-
依托单位:
Biosyntehsis and Properties of Copolyesters with 4-Hydroxyalkanoic Acid Unit
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批准号:16550133
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.05万
-
财政年份:2004
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负责人:KIMURA Hiroshi
-
依托单位:
Molecular mechanisms of chromatin formation and dynamics
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批准号:16084202
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$83.2万
-
财政年份:2004
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负责人:KIMURA Hiroshi
-
依托单位:
Regulation of gene expression and chromatin dynamics in living cells
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批准号:15370073
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.92万
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财政年份:2003
-
负责人:KIMURA Hiroshi
-
依托单位:
Hypoxic stress and atherosclerosis in patients with sleep apnea-hypopnea syndrome
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批准号:15590821
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
-
财政年份:2003
-
负责人:KIMURA Hiroshi
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依托单位:
Research on the generation mechanism of the behavior intelligence for a quadruped robot assisting the disabilities
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批准号:15500104
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.73万
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财政年份:2003
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负责人:KIMURA Hiroshi
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依托单位:
Pathogenesis on reactivation of viral infections in immunocompromised hosts and its prophylaxis and therapy.
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批准号:13670793
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.66万
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财政年份:2001
-
负责人:KIMURA Hiroshi
-
依托单位:
Assessment using hydra of endocrine disruptors contaminated in freshwater environment
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批准号:13680623
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.98万
-
财政年份:2001
-
负责人:KIMURA Hiroshi
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依托单位:
海外基金