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An informatics approach to the systematic understanding of a model disease

An informatics approach to the systematic understanding of a model disease
系统理解模型疾病的信息学方法
批准号:
17019065
负责人:
GOJOBORI Takashi
金额:
$60.29万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research on Priority Areas
财政年份:
2005
资助国家:
日本
项目状态:
已结题
起止时间:
2005 至 2009

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中文摘要
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英文摘要
We developed three-dimensional brain databases for human, mouse, and tunicate, which constitute the platform for constructing disease-information models of neuronal diseases. We also mirrored the three-dimensional mouse brain database of Paul Allen Brain Institute of the United States, and compared gene expression patterns in human and mouse brains. In particular, we clarified the protein-protein interaction network of the proteins associated with the Altzheimer's disease.
期刊论文(218)
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会议论文
DOI: 10.1038/455047a
发表时间: 2008-09-04
期刊: NATURE
影响因子: 64.8
作者: [Howe, Doug, Costanzo, Maria, Fey, Petra, Gojobori, Takashi, Hannick, Linda, Hide, Winston, Hill, David P., Kania, Renate, Schaeffer, Mary, St Pierre, Susan, Twigger, Simon, White, Owen, Rhee, Seung Yon]
通讯作者: Rhee, Seung Yon
DOI: 10.1093/nar/gkn724
发表时间: 2009-01
期刊: Nucleic acids research
影响因子: 14.9
作者: [Sugawara H, Ikeo K, Fukuchi S, Gojobori T, Tateno Y]
通讯作者: Tateno Y
DOI: 10.1093/nar/gkp1020
发表时间: 2010-01
期刊: Nucleic acids research
影响因子: 14.9
作者: [Yamasaki C, Murakami K, Takeda J, Sato Y, Noda A, Sakate R, Habara T, Nakaoka H, Todokoro F, Matsuya A, Imanishi T, Gojobori T]
通讯作者: Gojobori T
『月刊「公明」』3
《公明月刊》3
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [五條堀孝, 金城その子, Jose C. Clemente, 池尾一穂, 五條堀孝, Nakajima T, 五條堀孝, 五條堀孝, Yamagata T, 林崎良英, Nakayama Y, 五條堀孝]
通讯作者: 五條堀孝
184
    Evolution and Diversity in the system of development and differentiation
    • 批准号:
      12202005
    • 项目类别:
      Grant-in-Aid for Scientific Research on Priority Areas
    • 资助金额:
      $97.92万
    • 财政年份:
      2000
    • 负责人:
      GOJOBORI Takashi
    • 依托单位:
    Elucidation of the machinery of biodiversity on the basis of evolutionary genetics
    • 批准号:
      10836024
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.18万
    • 财政年份:
      1998
    • 负责人:
      GOJOBORI Takashi
    • 依托单位:
    Study on the DNA database and other biological databases
    • 批准号:
      10041187
    • 项目类别:
      Grant-in-Aid for Scientific Research (A).
    • 资助金额:
      $14.98万
    • 财政年份:
      1998
    • 负责人:
      GOJOBORI Takashi
    • 依托单位:
    Study on DNA and related bioinformatics databases
    • 批准号:
      07041155
    • 项目类别:
      Grant-in-Aid for international Scientific Research
    • 资助金额:
      $12.42万
    • 财政年份:
      1995
    • 负责人:
      GOJOBORI Takashi
    • 依托单位:
    海外基金