PREPARATION OF NONTOROMBOGENICHEMODIALYZER AND ITS PRECLINICAL EVALUATION
PREPARATION OF NONTOROMBOGENICHEMODIALYZER AND ITS PRECLINICAL EVALUATION
批准号:
06558122
负责人:
ISHIHARA Kazuhiko
金额:
$2.82万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Developmental Scientific Research (B)
财政年份:
1994
资助国家:
日本
项目状态:
已结题
起止时间:
1994 至 1995
中文摘要
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英文摘要
Hemocompatibility is one of the most important properties for homodialysis membranes. For improvement of the hemocompatibility on a cellulose dialysis membrane, modifications with new blood compatible phospholipid polymers were carried out. These methods incluuded a direct grafting of the phospholipid monomer on the membrane surface, coating the membrane surface with a water-soluble graft copolymer composed of a cellulose backbone and phospholipid polymer as a branch, and covalent bonding with a reactive phospholipid polymer on the membrane surface. These modified membranes could reduce protein adsorption, complement activation, and platelet adhesion on the surface without any adverse effects on the membrane perfomance.
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K.ISHIHARA,N.NAKABAYASHI: "HEMOCOMPATIBLE CELLULOSEDIALYSIS MEMBRANE MODIFIED WITH PHOSPHOLIPID POLYMER" ARTIFI ORGANS. 19 (12). 1215-1221 (1995)
K.Ishihara,N.Nakabayashi:“用磷脂聚合物修饰的血液相容性纤维素透析膜”人工器官。
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宮野龍之介,栗田公夫,石原一彦,渡辺昭彦,田中志信,中林宣男: "MPCポリマーによる血液透析膜の表面修飾" 東京医科歯科大学医用器材研究所報告. (印刷中). (1995)
Ryunosuke Miyano、Kimio Kurita、Kazuhiko Ishihara、Akihiko Watanabe、Shinobu Tanaka、Nobuo Nakabayashi:“用 MPC 聚合物对血液透析膜进行表面改性”东京医科齿科大学医疗设备研究所报告(1995 年)。
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K.ISHIHARA,K.FUKOMOTO,H.MIYAZAKI,N.NAKABAYASHI: "IMPROVEMENT OF THE HEMOCOMPATIBILTY ON A CELLULOSE HOLLOW FIBERS WITH A NOVEL BIOMEDICAL POLYMER HAVING PHOSPHOLIPID POLAR GROUP" ARTIFI ORGANS. 18 (8). 559-564 (1994)
K.ISHIHARA、K.FUKOMOTO、H.MIYAZAKI、N.Nakabayashi:“利用具有磷脂极性基团的新型生物医用聚合物改善纤维素空心纤维的血液相容性”Artifi 器官。
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K.ISHIHARA,H.MIYAZAKI,T.KUROSAKI,N.NAKABAYASHI: "IMPROVEMENT OF BLOOD COMPATIBILITY OF CELLULOSEDIALYSIS MEMBRANE3. SYNTHESIS AND PERFORMANCEOD WATER-SOLUBLECELLULOSE GRAFTED WITH PHOSPHOLIPID POLYMER AS COATING MATERIALSON CELLULOSE DIALYSIS MEMBRANE" J
K.Ishihara,H.MIYAZAKI,T.Kurosaki,N.Nakabayashi:“提高纤维素透析膜的血液相容性3.纤维素透析膜上接枝磷脂聚合物作为涂层材料的水溶性纤维素的合成及性能”J
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K.Ishihara: "Improvement of blood compatibility on cellulose dialysis membrane III.Syuthesis and performance of water-soluble cellulose grafted with phospholipid polymer" J.Biomed.Mater.Res.29. 181-188 (1995)
K.Ishihara:“纤维素透析膜上血液相容性的改善III.磷脂聚合物接枝的水溶性纤维素的合成和性能”J.Biomed.Mater.Res.29。
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共 17 条
Preparation of cell-based electron-generator
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批准号:22650107
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.14万
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财政年份:2010
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负责人:ISHIHARA Kazuhiko
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依托单位:
Preparation of biocompatible polymer nanoparticles as cell-function analysis biodevices
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批准号:21300176
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.73万
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财政年份:2009
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负责人:ISHIHARA Kazuhiko
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依托单位:
Study on a formulation of housing policy vision by character of area and renewal policy in suburb from view point of shrinking city
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批准号:18600009
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.43万
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财政年份:2006
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负责人:ISHIHARA Kazuhiko
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依托单位:
DETERMINATION OF MECHANISM FOR MOLECULAR ADHESION TO SOFT TISSUES AND MATERALS PREPARATION
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批准号:17300144
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.98万
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财政年份:2005
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负责人:ISHIHARA Kazuhiko
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依托单位:
Function of gastro-intestinal mucin-derived acidic oligosaccharaides recognized by anti-mucin monoclonal antibodies
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批准号:16590629
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.11万
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财政年份:2004
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负责人:ISHIHARA Kazuhiko
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依托单位:
Structure Control and Functions of Biocompatible Polymer Alloy as Biomaterials
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批准号:13480288
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.41万
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财政年份:2001
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负责人:ISHIHARA Kazuhiko
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依托单位:
A systematic development of monoclonal antibodies against mucins of digestive tract and their application to pathophysiological studies
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批准号:12670514
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.66万
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财政年份:2000
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负责人:ISHIHARA Kazuhiko
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依托单位:
PREPARATION OF NOVEL HEMOCOMPATIBLE HOLLOW FIBER MEMBRANE AND DEVICE FOR SAFETY BLOOD PURIFICATION HOME
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批准号:10558131
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.29万
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财政年份:1998
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负责人:ISHIHARA Kazuhiko
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依托单位:
PREPARATION OF NOVEL BIOMEDICAL POLYMERS HAUING BIOMEMBRANE-LIKE SURFACE AND RECOGNITION OF THEIR NON THROMBOGENIC
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批准号:09480250
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$5.44万
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财政年份:1997
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负责人:ISHIHARA Kazuhiko
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依托单位:
Mucus secretion studies using anti-gastric mucin monoclonal antibodies
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批准号:07670612
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.15万
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财政年份:1995
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负责人:ISHIHARA Kazuhiko
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依托单位:
Preparation of Novel Biocompatible polymeric Additives and Modification of Biomedical Materials Using the Additives
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批准号:07680934
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.41万
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财政年份:1995
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负责人:ISHIHARA Kazuhiko
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依托单位:
Measurement of rat gastric mucus secretion using ex-vivo gastric chamber system
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批准号:03670377
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$0.7万
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财政年份:1991
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负责人:ISHIHARA Kazuhiko
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依托单位:
海外基金