Novel Molecular Imprinting by Latex Polymerization-Basic Research for the Structure of Resin Surface-
乳胶聚合新型分子印迹-树脂表面结构的基础研究-
基本信息
- 批准号:07405038
- 负责人:
- 金额:$ 13.06万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Scientific Research (A)
- 财政年份:1995
- 资助国家:日本
- 起止时间:1995 至 1998
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
In recent years, the research area of design and synthesis of artificial host molecules is expanding focused by molecular recognition. We have developed a new method of molecular imprinting which produce a recognition site on the surface of latex particle.We started with a basic investigation of a system without template to connect the condition of emulsion and the structure of latex surface. The broadening of pKa was observed from proton titration of the resin. This result suggests the strong interaction between the functional groups and it is evidence that the carboxyl groups exist two dimensionally.We chose amino acid-derivatives as cationic organic template and synthesized imprinted resin. L-Phe-imprinted resin had high ability for adsorption of L-Phe. This result suggests the specific recognition site for L-Phe on the surface of the resin.We had used oleic acid as a functional surfactant, but there was possibility of missing of oleic acid from the resin. Then we designed and synthesized a new functional monomer possessing vinyl group. The form and character of the new resin was obviously different from the case of oleic acid. It is unknown what occurs during the surfactant was polymerized in the emulsion, but it was an interesting phenomenon.We tried an application to the membrane electrode-type ion sensor as a method for evaluation of imprinting effect. Molecular imprinted membrane was prepared by the polymerization after permeation of the salt of-functional monomer and organic cation into the membrane. This ion sensing membrane effectively responded to the templated ion, but it was not perfect Nernstian response.
近年来,以分子识别为中心的人工宿主分子的设计与合成研究领域不断扩大。我们发展了一种新的分子印迹方法,即在乳胶粒表面产生一个识别位点,我们从一个无模板体系的基础研究开始,将乳液条件和乳胶粒表面结构联系起来。从树脂的质子滴定中观察到pKa的加宽。这一结果表明了功能基团之间的强相互作用,证明了羧基是二维存在的。我们选择氨基酸衍生物作为阳离子有机模板,合成了印迹树脂。L-苯丙氨酸印迹树脂对L-苯丙氨酸有较强的吸附能力。这一结果表明,L-Phe在树脂表面上具有特异性识别位点,我们曾使用油酸作为功能表面活性剂,但存在油酸从树脂上丢失的可能性。然后设计合成了一种新的含乙烯基的功能单体。新树脂的形态和性质明显不同于油酸树脂。表面活性剂在乳液中聚合的过程中发生了什么尚不清楚,但这是一个有趣的现象。我们尝试将其应用于膜电极型离子传感器,作为评价印迹效果的方法。将功能单体的盐和有机阳离子渗透到膜中,通过聚合反应制备分子印迹膜。该离子传感膜有效地响应于模板离子,但它不是完美的能斯特响应。
项目成果
期刊论文数量(41)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
K.Tsukagoshi: "Surface Imprinting: Preparation of Metal Ion-Imprinted Resins by Use of Complexation at the Aqueous-Organic Interface" ACS SYMPOSIUM SERIES. 703. 251-263 (1998)
K.Tsukagoshi:“表面印迹:通过在水-有机界面络合制备金属离子印迹树脂”ACS 研讨会系列。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
Tohru Miyajima: "A Physicochemical Study on the Origin of the Imprinting Effect" Recognition with Imprinted Polymers. (印刷中). (1998)
Tohru Miyajima:“印迹效应起源的物理化学研究”识别印迹聚合物(1998 年)。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
Y.Koide et al.: "Selective Adsorption of Metal Ions to Surface-Template Resins Prepared by Emulsion Polymerization Using 10-(p-Vinylphenyl) decanoic Acid" Bull.Chem.Soc.Jpn.69. 125-130 (1996)
Y.Koide等人:“使用10-(对乙烯基苯基)癸酸通过乳液聚合制备的表面模板树脂选择性吸附金属离子”Bull.Chem.Soc.Jpn.69。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
I.Fujiwara et al.: "Ferrocyanide-Templated Resins Prepared by Surface Template Polymerization" Anal.Sci.12. 545-549 (1996)
I.Fujiwara 等人:“通过表面模板聚合制备的亚铁氰化物模板树脂”Anal.Sci.12。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
K.Tsukagoshi et al.: "Preparation and Characterization of Polymer Microspheres Which Have Specific Binding Ability for Saccharide Molecules" Anal.Sci.12. 721-726 (1996)
K.Tsukagoshi 等人:“对糖分子具有特异性结合能力的聚合物微球的制备和表征”Anal.Sci.12。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
TAKAGI Makoto其他文献
TAKAGI Makoto的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('TAKAGI Makoto', 18)}}的其他基金
Nanofabrication and Strengthening of Silicon Single Crystal by UsingSPM
利用SPM对硅单晶进行纳米加工和强化
- 批准号:
22560124 - 财政年份:2010
- 资助金额:
$ 13.06万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Preparation of Tribological Materials for Microelectromechanical systems
微机电系统摩擦学材料的制备
- 批准号:
13650766 - 财政年份:2001
- 资助金额:
$ 13.06万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Gene Detection by Light-to-electric Converting Intercalator and Its Application to DNA
光电转换嵌入剂基因检测及其在DNA中的应用
- 批准号:
12305054 - 财政年份:2000
- 资助金额:
$ 13.06万 - 项目类别:
Grant-in-Aid for Scientific Research (A)
High-throughput Screening of Proteins by Electrochemical Protein Chip
电化学蛋白质芯片高通量筛选蛋白质
- 批准号:
12555236 - 财政年份:2000
- 资助金额:
$ 13.06万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Tribology of Nanostructured Materials for the Application to the Micromachine
纳米结构材料摩擦学在微机械中的应用
- 批准号:
11650726 - 财政年份:1999
- 资助金额:
$ 13.06万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Establishment of Fundamental Technique of Electrode Surface Modification for Development on Molecularly Imprinted Sensor
分子印迹传感器开发电极表面修饰基础技术的建立
- 批准号:
09555265 - 财政年份:1997
- 资助金额:
$ 13.06万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Development of Novel Metal Ion Selective Ion-exchange Resin Based on Surface Template Polymerization
基于表面模板聚合的新型金属离子选择性离子交换树脂的研制
- 批准号:
06555256 - 财政年份:1994
- 资助金额:
$ 13.06万 - 项目类别:
Grant-in-Aid for Scientific Research (A)
有機電解質の薄膜を用いる交流検出型気体センサの研究
有机电解质薄膜交流检测型气体传感器的研究
- 批准号:
01850172 - 财政年份:1988
- 资助金额:
$ 13.06万 - 项目类别:
Grant-in-Aid for Developmental Scientific Research (B).
Development of ion-permselective piezodialysis membranes
离子选择性渗透压电渗析膜的开发
- 批准号:
60470066 - 财政年份:1985
- 资助金额:
$ 13.06万 - 项目类别:
Grant-in-Aid for General Scientific Research (B)
相似海外基金
ウリ科作物における有機汚染物質の立体選択的な蓄積メカニズムの解明
葫芦科作物有机污染物立体选择性积累机制的阐明
- 批准号:
23K13884 - 财政年份:2023
- 资助金额:
$ 13.06万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Etiology and Outcomes of Meningitis in Rural, Northern Uganda
乌干达北部农村地区脑膜炎的病因和结果
- 批准号:
10543219 - 财政年份:2022
- 资助金额:
$ 13.06万 - 项目类别:
Etiology and Outcomes of Meningitis in Rural, Northern Uganda
乌干达北部农村地区脑膜炎的病因和结果
- 批准号:
10693970 - 财政年份:2022
- 资助金额:
$ 13.06万 - 项目类别:
Understanding the Mechanism of Soil Particle Aggregation Enhancement by Natural Latex and its Application to Soil Erosion Control Technology
天然乳胶增强土壤颗粒聚集机理及其在水土流失防治技术中的应用
- 批准号:
22K19224 - 财政年份:2022
- 资助金额:
$ 13.06万 - 项目类别:
Grant-in-Aid for Challenging Research (Exploratory)
Developing a reproductive health curriculum for adolescent girls with physical disabilities
为身体残疾的少女制定生殖健康课程
- 批准号:
10523587 - 财政年份:2022
- 资助金额:
$ 13.06万 - 项目类别:
Enhancing Latex-based Coatings and Pressure Sensitive Adhesives with Carboxylated Cellulose Nanocrystals
用羧化纤维素纳米晶体增强乳胶基涂料和压敏粘合剂
- 批准号:
560215-2020 - 财政年份:2022
- 资助金额:
$ 13.06万 - 项目类别:
Alliance Grants
Translating Lp(a) biology to clinical applications
将 Lp(a) 生物学转化为临床应用
- 批准号:
10446215 - 财政年份:2022
- 资助金额:
$ 13.06万 - 项目类别:
Translating Lp(a) biology to clinical applications
将 Lp(a) 生物学转化为临床应用
- 批准号:
10593157 - 财政年份:2022
- 资助金额:
$ 13.06万 - 项目类别:
PCB-induced priming of microglial activity across sexes and development
PCB诱导的跨性别小胶质细胞活性启动和发育
- 批准号:
10513248 - 财政年份:2022
- 资助金额:
$ 13.06万 - 项目类别:
Developing a reproductive health curriculum for adolescent girls with physical disabilities
为身体残疾的少女制定生殖健康课程
- 批准号:
10709529 - 财政年份:2022
- 资助金额:
$ 13.06万 - 项目类别: