Cohort study of morbidity and mortality from lifestyle-related diseases among Japanese dietitians

日本营养师生活方式相关疾病发病率和死亡率的队列研究

• 批准号: 19390177
• 负责人: TOKUDOME Shinkan
• 金额: $ 12.23万
• 依托单位: Nagoya City University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2007
• 资助国家: 日本
• 起止时间: 2007 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19390177/
• 关键词: 栄養士; 生活習慣; 食生活; 生活習慣病; 罹患・死亡; コホート研究

During 1999-2000, we constructed JADE (Japanese Dietitians' Epidemiologic) study cohort consisting of 11,630 dietitians/registered dietitians, including members of 26 Prefectural Branches of the Japanese Dietetic Association, and alumni members of 6 colleges/universities for dietitians. After obtaining their informed consent, we collected baseline information on dietary habits and lifestyle administering a validated semi-quantitative food frequency questionnaire (SQFFQ) and lifestyle questionnaire (LSQ). We studied morbidity of cancer and mortality from lifestyle-related diseases and investigated any associations between dietary habits and lifestyle with risk of or mortality from lifestyle-related diseases. In 2007, we made an interim survey administering an abbreviated LSQ and a short FFQ and studied changes from baseline, including anthropometric conditions, histories of diseases and dietary habits. From this study, we confirmed 16 deaths (6 men and 10 women) and determined each underlying cause of death. Using sex- and age-specific mortality rates of Japan in 2003 and person-years of the study subjects, we calculated the expected number of deaths and computed ratios of observed /expected number of deaths. The O/E ratios for cancers and all causes were less than one with statistical significance (p<0.01).

在1999-2000年期间，我们构建了由11,630名注册营养师/营养师组成的JADE（日本营养师流行病学）研究队列，其中包括26个日本饮食协会县分会的会员和6所高等院校的校友营养师。在获得他们的知情同意后，我们通过半定量食物频率问卷（SQFFQ）和生活方式问卷（LSQ）收集饮食习惯和生活方式的基线信息。我们研究了癌症发病率和生活方式相关疾病的死亡率，并调查了饮食习惯和生活方式与生活方式相关疾病的风险或死亡率之间的关系。2007年，我们进行了一项临时调查，使用了一个简短的LSQ和一个简短的FFQ，研究了从基线开始的变化，包括人体测量条件、疾病史和饮食习惯。从这项研究中，我们确认了16例死亡（6名男性和10名女性），并确定了每个潜在的死亡原因。利用2003年日本按性别和年龄分列的死亡率以及研究对象的人年，我们计算了预期死亡人数，并计算了观察死亡人数/预期死亡人数的比率。肿瘤及所有原因的O/E比均小于1，差异均有统计学意义（p<0.01）。

项目成果

Lifestyle-related risk factors for stomach cancer in northeast Thailand.

• 发表时间: 2008
• 期刊: Asian Pacific journal of cancer prevention : APJCP
• 作者: K. Suwanrungruang;S. Sriamporn;S. Wiangnon;Dhanes Rangsrikajee;A. Sookprasert;Nakorn Thipsuntornsak;P. Sa

Eicosapentaenoic acid has a preventive effect on the recurrence of nephrolithiasis

二十碳五烯酸对肾结石复发有预防作用

• 发表时间: 2008
• 期刊: Urol Int 81(2)
• 作者: Yasui T;Suzuki S;Itoh Y;Tozawa K;Tokudome S;Kohri K
• 通讯作者: Kohri K

Depression, Inflammation, and Pain in Patients With Rheumatoid Arthritis

• DOI: 10.1002/art.24647
• 发表时间: 2009-08-15
• 期刊: ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH
• 作者: Kojima, Masayo;Kojima, Toshihisa;Ishiguro, Naoki
• 通讯作者: Ishiguro, Naoki

Serum concentrations of fatty acids and colorectal adenoma risk: a case-control study in Japan.

• 发表时间: 2008
• 期刊: Asian Pacific journal of cancer prevention : APJCP
• 作者: Reza Ghadimi;K. Kuriki;S. Tsuge;Emiru Takeda;N. Imaeda;Sadao Suzuki;Asuka Sawai;K. Takekuma;A. Hosono;Y. Tokudome;C. Goto;Imaneh Esfandiary;H. Nomura;S. Tokudome

Strong interaction between the effects of alcohol consumption and smoking on esophageal squamous cell carcinoma among individuals with ADH1B and/or ALDH2 risk alleles.

在携带 ADH1B 和/或 ALDH2 风险等位基因的个体中，饮酒和吸烟对食管鳞状细胞癌的影响之间存在很强的相互作用。

• 发表时间: 2010
• 期刊: Gut 59
• 作者: Tanaka;F.;Yamamoto;K.;Suzuki;S.;Inoue;H.;Tsurumaru;M.;Kajiyama;Y.;Kato;K.;Igaki;H.;Furuta;K.;Fujita;H.;Tanaka;T.;Tanaka;Y.;Kawashima;Y.;Natsugoe;S.;Setoyama;T.;Tokudome;S.;Mimori;K.;Haraguchi;N.;Ishii;H.;Mori;M.
• 通讯作者: M.