Development of central auditory systemand and plasticity of inner ear in congenital deaf model rat
Development of central auditory systemand and plasticity of inner ear in congenital deaf model rat
批准号:
19591961
负责人:
ITO Makoto
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009
中文摘要
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英文摘要
先天聾モデルラットを作成し、聴覚中枢の投射と蛋白発現の変化について検討した。下位中枢では下丘投射の減少がみられたが、上位中枢では大きな変化はみられなかった。カルシウム結合蛋白の発現に変化がみられ、Hearing onsetが起きないということが、聴覚中枢の発達に影響をおよぼす事が明らかとなった。また突発性難聴において、抗酸化ビタミンEとCを従来の治療に併用する事で、著明な治癒率の向上が得られた。これは虚血再灌流障害を予防する効果による可能性がある。
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上気道感染症と咽頭細菌叢保育園児の上咽頭細菌叢の変遷
上呼吸道感染与咽部菌群 幼儿鼻咽部菌群变化
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Hisashi Sugimoto, Makoto Ito, Tomokazu Yoshizaki, 伊藤真人, 伊藤真人, 伊藤真人]
通讯作者:
伊藤真人
ラット片側先天聾モデルにおける下丘への投射の変化
大鼠单侧先天性耳聋模型下丘投影的变化
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[波多野都, 伊藤真人, 古川仭]
通讯作者:
古川仭
よくわかる病態生理14耳鼻咽喉科疾患
通俗易懂的病理生理学14种耳鼻喉科疾病
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Miyako Hatano, Makoto Ito, 伊藤真人]
通讯作者:
伊藤真人
DOI:
10.3109/00016480802642096
发表时间:
2009-11-01
期刊:
ACTA OTO-LARYNGOLOGICA
影响因子:
1.4
作者:
[Ito, Makoto, Hatano, Miyako, Yoshizaki, Tomokazu]
通讯作者:
Yoshizaki, Tomokazu
Neuroprotective Effects of TJ-23 on Adult Rat Motoneurons Following Periheral Facial Nerve Axotomy
TJ-23 对成年大鼠周围面神经轴突切除术后运动神经元的神经保护作用
DOI:
--
发表时间:
2007
期刊:
Otolaryngol Head Neck Surg 136
影响因子:
--
作者:
[M Ito, M Ohbayashi, M Furukawa, S Okoyama]
通讯作者:
S Okoyama
共 40 条
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Coexistence phenomena of chemical-bonding-like structures in neutron excess systems
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Paleohydrology in greenhouse and icehouse stages
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Investigation of Japanese and German Idioms with part of body
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Sphingolipid Engineering Using Marine Resources
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EFFECTIVE ENFORCEMENT OF JUDGMENT DEBTS.
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Effects of three dimensional electrical properties on the mechanisms of initiation, maintenance, and termination of atrial fibrillation ; clinical and computer simulation study
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