Roll of interleukin-32 in inflammatory bone resorption caused by periodontopathic bacterium
Roll of interleukin-32 in inflammatory bone resorption caused by periodontopathic bacterium
白细胞介素32在牙周病细菌引起的炎性骨吸收中的作用
批准号：
19592123
负责人：
TSUJISAWA Toshiyuki
金额：
$2.83万
依托单位：
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2007
资助国家：
日本
项目状态：
已结题
起止时间：
2007 至 2009
中文摘要
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英文摘要
We examined whether lipopolysaccaride (LPS) derived from Aggregatibacter actinomycetemcomitans, one of periodontopathic bacteria, induce expression of interlukin-32. We also analyzed the induction mechanism of IL-32 in human monocyte. Scince an inhibitor of NF-kB, one of downstream signaling of Toll-like receptor 4, inhibits the expression of IL-32, it was suggested that NF-kB activation was involved in the induction of IL-32 by LPS.
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会议论文
DOI：
10.1016/j.joen.2007.05.015
发表时间：
2007-10-01
期刊：
JOURNAL OF ENDODONTICS
影响因子：
4.2
作者：
[Nomiyama, Kimiko, Kitamura, Chiaki, Nishihara, Tatsuji]
通讯作者：
Nishihara, Tatsuji
Induction of anti- Porphyromanas gingivalis antibody by tonsillar application
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批准号：10671704
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项目类别：Grant-in-Aid for Scientific Research (C)
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资助金额：$1.79万
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财政年份：1998
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负责人：TSUJISAWA Toshiyuki
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依托单位：
海外基金
