Single-cell on-time molecular analysis by hyper-sensitive video-mass scope

我们建立了世界上第一个活的单细胞质谱仪，它可以在10分钟内在显微镜下详尽地分析活的单细胞感兴趣点的微吸组分中的分子。活体肥大细胞胞质和细胞器中的分子分布和代谢、分化神经元细胞的分子交换、植物活体细胞的分子生物合成和光响应、单个肝细胞的药物代谢，甚至单个汗腺中仅一滴汗液中的分子含量，都被成功地分析出来，显示了这种新的做梦方法的丰硕性能和潜力。

We have established“the live single cell mass spectrometry”first in the world by which molecules in a micro-sucked components from interest points of a live single cell can be analyzed exhaustively and directly under microscopic observation within 10 min. Molecular distribution and metabolism in cytoplasm and organelle in a live mast cell, molecular interchanging of differentiating neuron cell, molecular biosynthesis and photo response of live plant cells, drug metabolism of a single hepatic cell, and even molecular contents in only one drop from a single sweat gland have all been analyzed successfully to show the fruitful performance and potential of this new dreaming method.