Experimental evidence of in situ capture of endothelial progenitor cells on luminal surface of artificial grafts in bloodstream on porcein model.
Experimental evidence of in situ capture of endothelial progenitor cells on luminal surface of artificial grafts in bloodstream on porcein model.
批准号:
20300171
负责人:
MATSUDA Takehisa
金额:
$12.81万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
This study aims at in situ capture of endothelial progenitor cells (EPCs) on blood-contacting surfaces of cardiovascular devices in bloodstream. Among various cell surface receptor/legend pairs, only surface-bound VEGF/VEGF receptor pair induced adhesion, proliferation, and differentiation of EPCs in vitro. VEGF-bound stents and artificial grafts generated EPC adhesion and colonization, followed by endothelialization on porcein model. Thus, our prototype surface architecture to propose new concept of providing nonthrambogenic potential on blood-contacting devices.
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Antibody-bound cell microarray for immunophenotyping: surface modification and lymphocyte subpopulations.
用于免疫表型分析的抗体结合细胞微阵列:表面修饰和淋巴细胞亚群。
DOI:
10.1002/jbm.b.31139
发表时间:
2008
期刊:
Journal of biomedical materials research. Part B, Applied biomaterials
影响因子:
--
作者:
[Fujii,Yasuo, Anderson,JamesM, Matsuda,Takehisa]
通讯作者:
Matsuda,Takehisa
Simultaneous Processing of Fibril Formation and Cross-Linking Improves Mechanical Properties of Collagen
原纤维形成和交联的同时处理可提高胶原蛋白的机械性能
DOI:
--
发表时间:
2008
期刊:
Biomacromolecules 9(3)
影响因子:
--
作者:
[S. Yunoki, T. Matsuda]
通讯作者:
T. Matsuda
DOI:
10.1002/jbm.a.31660
发表时间:
2008-07
期刊:
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
影响因子:
4.9
作者:
[Jones, Jacqueline A., Qin, L. Abby, Meyerson, Howard, Kwon, Il Keun, Matsuda, Takehisa, Anderson, James M.]
通讯作者:
Anderson, James M.
International Review of Thrombosis
国际血栓形成综述
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[西村智, 長崎実佳]
通讯作者:
長崎実佳
Robotics-based Fabrication of Vascular Graft.
基于机器人的血管移植物制造。
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Shimizu S, Shishido T, Une D, Kamiya A, Kawada T, Sano S, Sugimachi M., 松田武久]
通讯作者:
松田武久
共 15 条
Toward Development of in-situ Endothelialized Artificial Graft : Hydrodynamic Shear Stress Dependent Retention of Endothelial Cells Adhered to a Vascular Endothelial Growth Factor-Fixed Surface
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批准号:18300165
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.93万
-
财政年份:2006
-
负责人:MATSUDA Takehisa
-
依托单位:
Mechanobiology in tissue formation and robotic engineering of functional tissues
-
批准号:17076012
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$44.1万
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财政年份:2005
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负责人:MATSUDA Takehisa
-
依托单位:
High-performance Stent Technology
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批准号:15200038
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$30.28万
-
财政年份:2003
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负责人:MATSUDA Takehisa
-
依托单位:
Develop of High Performance Stents
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批准号:12358017
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项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$19.1万
-
财政年份:2000
-
负责人:MATSUDA Takehisa
-
依托单位:
Fundamental study on small-diameter vascular graft incorporated with new design concepts of mechanical compatibility and tissue morphogenesis.
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批准号:12470277
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.24万
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财政年份:2000
-
负责人:MATSUDA Takehisa
-
依托单位:
Design of Extracellular Space
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批准号:09480260
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.54万
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财政年份:1997
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负责人:MATSUDA Takehisa
-
依托单位:
Tissue-Engineered Cardiovascular Tissues
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批准号:09357014
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$11.46万
-
财政年份:1997
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负责人:MATSUDA Takehisa
-
依托单位:
Tissue Engineering of Vascular Wall Reconstruction : Fundamentals & Application
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批准号:07044303
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$2.94万
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财政年份:1995
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负责人:MATSUDA Takehisa
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依托单位:
Development of Small-Diameter Artificial Graff via Multifaceted Appproaches
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批准号:06557075
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$8.64万
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财政年份:1994
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负责人:MATSUDA Takehisa
-
依托单位:
Mechanical Stress-Loading on Cellular Responses of Vascular Cell Types
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批准号:07458241
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.74万
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财政年份:1994
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负责人:MATSUDA Takehisa
-
依托单位:
Novel Synthetic Surgical Adhesive Incorporated with Biomechanical Concept
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批准号:04557055
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项目类别:Grant-in-Aid for Developmental Scientific Research (B)
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资助金额:$4.93万
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财政年份:1992
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负责人:MATSUDA Takehisa
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依托单位:
Development of a New Transvenous Patent Ductus Arterious Occlusion Technique
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批准号:02557043
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项目类别:Grant-in-Aid for Developmental Scientific Research (B)
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资助金额:$3.01万
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财政年份:1990
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负责人:MATSUDA Takehisa
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依托单位:
Development of Hybrid Artificial Graft With Hierarchical Tissue Structure
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批准号:01570797
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1989
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负责人:MATSUDA Takehisa
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依托单位:
Multiphasic studies on mechamistic asrects of Biocompatiblity of Materials used far Cardiouascular Devices
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批准号:61480303
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$3.84万
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财政年份:1986
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负责人:MATSUDA Takehisa
-
依托单位:
Development of Control-Release Materials and Its Applications to Cardiovascular Artificial Organs
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批准号:60870048
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项目类别:Grant-in-Aid for Developmental Scientific Research
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资助金额:$1.92万
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财政年份:1985
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负责人:MATSUDA Takehisa
-
依托单位:
海外基金