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Study on the relationship between amino acid substitutions and natural selection taking into account the three dimensional structure of proteins

Study on the relationship between amino acid substitutions and natural selection taking into account the three dimensional structure of proteins
考虑蛋白质三维结构的氨基酸取代与自然选择的关系研究
批准号:
20570008
负责人:
SUZUKI Yoshiyuki
金额:
$1.58万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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中文摘要
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英文摘要
A phylogenetic window analysis method was developed for detecting chronological changes in natural selection. CpG hypermutability was also taken into account for detecting natural selection. It was clarified that converting the alignment of amino acid sequences into that of codon sequences causes biased inference of natural selection. Influenza virus appeared to escape from host immune responses continuously in the tropical region. A method for detecting reassortment from a large number of genomic sequences was also developed.
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会议论文
Information Integration Project and H-Invitational 2 Consortium : The H-invitational database (H-InvDB), a comprehensive annotation resource for human genes and transcripts.
信息集成项目和 H-Invitational 2 联盟:H-invitational 数据库 (H-InvDB),人类基因和转录本的综合注释资源。
DOI: --
发表时间: 2008
期刊: Nucleic Acids Research 36
影响因子: --
作者: [KaiQin Xu, Lian-hui Qi, Yoshitaka Ebie, Yuhei Inamori, Ryuichi Sudo, 柴尾晴信, Genome]
通讯作者: Genome
CpG高突然変異率を考慮したアミノ酸配列レベルに働く自然選択圧検出法の開発
考虑到高 CpG 突变率,开发在氨基酸序列水平上工作的自然选择压力检测方法
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [深谷肇一, 野田隆史, 仲岡雅裕, 山本智子, 堀正和, 奥田武弘, 熊谷直喜, 島袋寛盛, 鈴木善幸, Kato N., 野田隆史, 鈴木善幸, Kotani K., 辻野昌広・野田隆史・山本智子・仲岡雅裕・堀正和, 鈴木善幸]
通讯作者: 鈴木善幸
ゲノム進化学の新展開
基因组进化的新进展
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Inoue, T, 鈴木善幸]
通讯作者: 鈴木善幸
ウイルスと遺伝学について
关于病毒和遗传学
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Serizawa, H., Amemiya, T., Itoh, K., 鈴木善幸]
通讯作者: 鈴木善幸
53
    Molecular biological investigation about the effect of heavy-ion beam on normal brain
    • 批准号:
      22791167
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.5万
    • 财政年份:
      2010
    • 负责人:
      SUZUKI Yoshiyuki
    • 依托单位:
    Basical study for curing malignant brain tumor with carbon-ion beam therapy
    • 批准号:
      20790877
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.58万
    • 财政年份:
      2008
    • 负责人:
      SUZUKI Yoshiyuki
    • 依托单位:
    Study on Development of Design Method for Traditional Wooden Buildings Based on Structural Details
    Study on seismic design and enhancement design of traditional wooden buildings in preparation for large earthquakes
    • 批准号:
      16201039
    • 项目类别:
      Grant-in-Aid for Scientific Research (A)
    • 资助金额:
      $25.63万
    • 财政年份:
      2004
    • 负责人:
      SUZUKI Yoshiyuki
    • 依托单位:
    海外基金