The development of novel immune gene therapy for chronic viral infections.
The development of novel immune gene therapy for chronic viral infections.
批准号:
20591279
负责人:
TAUCHI Hisamichi
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
需要为患有慢性活动性EB病毒感染和病毒相关噬血细胞综合征等顽固性感染的儿童开发新的治疗方法。建立了EB病毒特异性的人CD_4、CD_8 T淋巴细胞。我们证实了EB病毒特异性的CD4、CD8T淋巴细胞对LCL细胞系具有细胞毒作用。
英文摘要
Development of new treatments for children with intractable infections such as chronic active EB virus infection and virus-associated hemophagocytic syndrome have been demanded. We establishmed EB virus specific human CD4, CD8 T lymphocyte. We confirmed the EB virus specific CD4, CD8 T lymphocyte have cytotoxicity for LCL cell line.
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DOI:
10.1007/s12185-010-0558-0
发表时间:
2010-05-01
期刊:
INTERNATIONAL JOURNAL OF HEMATOLOGY
影响因子:
2.1
作者:
[Imamura, Toshihiko, Sato, Takashi, Morimoto, Akira]
通讯作者:
Morimoto, Akira
Reconstruction using a frozen bone method for osteosarcoma of the talus. A case report and review of the literature.
采用冷冻骨法重建距骨骨肉瘤。
DOI:
--
发表时间:
2009
期刊:
Anticancer Res. 29
影响因子:
--
作者:
[Sakayama K, Kidani T, Tauchi H, 他6人]
通讯作者:
他6人
DOI:
10.1186/1743-422x-7-91
发表时间:
2010-05-10
期刊:
VIROLOGY JOURNAL
影响因子:
4.8
作者:
[Murakami, Yuichi, Tanimoto, Kazushi, Yasukawa, Masaki]
通讯作者:
Yasukawa, Masaki
Reconstruction using a frozen bone method for osteosarcoma of the talus. A case report and review of the literature
采用冷冻骨法重建距骨骨肉瘤。
DOI:
--
发表时间:
2009
期刊:
Anticancer Res. 29
影响因子:
--
作者:
[Sakayama K, Kidani T, Sugawara Y, Tauchi H, Fujibuchi T, Tanji N, Yamamoto H, Tsuchiya H]
通讯作者:
Tsuchiya H
Clinical features and outcome of MLL gene rearranged acute lymphoblastic leukemia in infants with additional chromosomal abnormalities other than 11q23 translocation
11q23 易位以外其他染色体异常婴儿 MLL 基因重排急性淋巴细胞白血病的临床特征和结局
DOI:
--
发表时间:
2008
期刊:
Leuk Res 32巻10号
影响因子:
--
作者:
[H. Tauchi, D. Tomizawa, M. Eguchi, M. Eguchi-Ishimae, K. Koh, M. Hirayama, N. Miyamura, N. Kinukawa, Y. Hayashi, K. Horibe, E. Ishii]
通讯作者:
E. Ishii
共 19 条
Study on immunotherapy of the intractable EB virus infectious disease using the humanized animal model
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批准号:23591572
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.08万
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财政年份:2011
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负责人:TAUCHI Hisamichi
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依托单位:
海外基金