Genetic analysis of glioblastoma cancer stem cell with special reference to chronological and spatial change
Genetic analysis of glioblastoma cancer stem cell with special reference to chronological and spatial change
批准号:
20591708
负责人:
HAYASHI Yutaka
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
To evaluate the specific factors in tumorigenesis of the glioblastoma, especially in chronological and spatial character, several genes expressions and mutations were analyzed. Among the integrins that could be related with invasion, the alpha 3 subunit had a significantly higher expression level in tumor stem cells. The alpha 3 subunit of integrin could play an important role in the tumor invasion. Furthermore, during a course of tumor progression, FAS and TP53 mutation were detected. These genetic alterations could be related with tumor progression with a malignant transformation.
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Ependymoma and choroid plexus papilloma as synchronous multiple neuroepithelial tumor in the same patient : a case report and review of literature
室管膜瘤和脉络丛乳头状瘤同时发生在同一患者的多发性神经上皮肿瘤一例报告并文献复习
DOI:
--
发表时间:
2010
期刊:
Neurosurgery (in press)
影响因子:
--
作者:
[Hayashi Y., et al]
通讯作者:
et al
Frequent single nucleotide polymorphism (SNP) of BCL10 and association with poor prognosis in primary intracranial germ cell tumors
BCL10 频繁的单核苷酸多态性 (SNP) 与原发性颅内生殖细胞肿瘤的不良预后相关
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[林裕, 渡邉卓也, 中田光俊, 喜多大輔, 林康彦, 内山尚之, 濱田潤一郎]
通讯作者:
濱田潤一郎
Secondary anaplastic astrocytomadeveloping in a young adult withautoimmune lymphoproliferativesyndrome(ALPS)
患有自身免疫性淋巴增殖综合征 (ALPS) 的年轻成人继发性间变性星形细胞瘤
DOI:
10.1111/j.1365-2990.2010.01123.x
发表时间:
2011
期刊:
Neuropathol ApplNeurobiol
影响因子:
--
作者:
[Kita, D., Hayashi, Y., Watanabe, T., Korshunov, A., von Deimling, A., Nakada, M., Kasahara, Y., Zen, Y. and Hamada, J]
通讯作者:
J
DOI:
10.1016/j.clineuro.2008.07.010
发表时间:
2009-01-01
期刊:
CLINICAL NEUROLOGY AND NEUROSURGERY
影响因子:
1.9
作者:
[Hayashi, Yutaka, Uchiyama, Naoyuki, Hamada, Jun-ichiro]
通讯作者:
Hamada, Jun-ichiro
巨大insular glioma摘出の問題点
巨大岛状胶质瘤摘除的问题
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[林裕, 中田光俊, 喜多大輔, 佐野宏樹, 田中慎吾, 長谷川貴之, 林康彦, 内山尚之, 濱田潤一郎]
通讯作者:
濱田潤一郎
共 24 条
Role and contribution of rural society for peacebuilding
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批准号:16H07365
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项目类别:Grant-in-Aid for Research Activity Start-up
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资助金额:$1.16万
-
财政年份:2016
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负责人:HAYASHI Yutaka
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依托单位:
Can tsunami be monitored from the space? -Tsunami detectability of the satellite altimetry mission
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批准号:20510173
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
-
财政年份:2008
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负责人:HAYASHI Yutaka
-
依托单位:
Molecular Characterization of Patched-associated Rhabdomyosarcoma by Conditional Gene Targeting
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批准号:15390319
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.02万
-
财政年份:2003
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负责人:HAYASHI Yutaka
-
依托单位:
Molecular genetic analysis and establishment of tailor-maid therapy for malignant brain tumors.
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批准号:12671345
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
-
财政年份:2000
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负责人:HAYASHI Yutaka
-
依托单位:
Identification of neuroblastoma associating genes and application of medical treatment using gene manipulation in an individual
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批准号:12470164
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$8.9万
-
财政年份:2000
-
负责人:HAYASHI Yutaka
-
依托单位:
Deletion mapping of chromosome band 14q32 for isolation and characterization of the putative tumor related gene in human neuroblastoma
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批准号:09470386
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.38万
-
财政年份:1997
-
负责人:HAYASHI Yutaka
-
依托单位:
SIGNIFICANCE OF NEUROPEPTIDE Y IN EARLY DIAGNOSIS AND PATHOGENETIC ANALYSIS OF NEUROBLASTOMA
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批准号:06454503
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.1万
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财政年份:1994
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负责人:HAYASHI Yutaka
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依托单位:
Hyperplasia of distal airway epithelium due to aging among residents in the area where the incidence of lung cancer is high.
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批准号:03454165
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$2.05万
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财政年份:1991
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负责人:HAYASHI Yutaka
-
依托单位:
SIGNIFICANCE OF NEUROPEPTIDE Y IN EARLY DIAGNOSIS AND AS A PROGNOSTIC FACTOR OF NEUROBLASTOMA
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批准号:03670577
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1991
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负责人:HAYASHI Yutaka
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依托单位:
フローサイトメトリーによる小児癌の悪性度の判定と抗癌剤スクリーニングに関する研究
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批准号:61570601
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1986
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负责人:HAYASHI Yutaka
-
依托单位:
海外基金