A study of chemoprevention of prostate cancer with statins in a knock-in mouse prostate cancer model
A study of chemoprevention of prostate cancer with statins in a knock-in mouse prostate cancer model
批准号:
20591859
负责人:
SAKAI Hideki
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
Transrectal ultrasonography with an endovascular ultrasound probe allowed longitudinal monitoring of in situ tumor growth in the genetically engineered mouse prostate cancer model, PSP-KIMAP. Although preventative effects of statins in prostate cancer were not successfully analyzed, our data suggest that a non-receptor protein-tyrosine kinase, c-Fes may be involved in the development and progression of prostate cancer via cell proliferation. We speculate that c-Fes is a possible target in the treatment and chemoprevention of prostate cancer.
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前立腺癌の化学予防
前列腺癌的化学预防
DOI:
--
发表时间:
2010
期刊:
癌と化学療法 37巻、1号
影响因子:
--
作者:
[榎田英樹, ほか, 酒井英樹]
通讯作者:
酒井英樹
前立腺癌におけるc-Fesの発現と臨床病理学的特徴や増殖、アポトーシスとの関連
前列腺癌c-Fes表达与临床病理特征、增殖、凋亡的关系
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[小原航, 高田亮, 藤岡知昭, 宮田康好]
通讯作者:
宮田康好
前立腺癌におけるFesの臨床病理学的意義
Fes 在前列腺癌中的临床病理意义
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[呉秀賢, 常森寛行, 乾政志, 杉元幹史, 筧善行, 渡邉慎一]
通讯作者:
渡邉慎一
前立腺癌発症ノックインマウスにおける血管内超音波プローブを用いた経直腸的超音波断層法の有用性
使用血管内超声探头进行经直肠超声断层扫描在患有前列腺癌的敲入小鼠中的效用
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Ito K, 他, 丸田大]
通讯作者:
丸田大
DOI:
10.1007/s00432-009-0718-x
发表时间:
2010-05
期刊:
Journal of Cancer Research and Clinical Oncology
影响因子:
3.6
作者:
[Shin‐ichi Watanabe;Y. Miyata;S. Kanda;T. Iwata;Tomayoshi Hayashi;H. Kanetake;H. Sakai]
通讯作者:
Shin‐ichi Watanabe;Y. Miyata;S. Kanda;T. Iwata;Tomayoshi Hayashi;H. Kanetake;H. Sakai
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A study for treatment of castration-resistant prostate cancer targeting PGE2 receptors in cancer associated stromal cells
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批准号:16K11012
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.08万
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财政年份:2016
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负责人:SAKAI Hideki
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依托单位:
Elucidation of the molecular components and regulatory mechanism of anion channels controlling the cell homeostasis and death
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批准号:15K15029
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
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负责人:SAKAI Hideki
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依托单位:
Chemoprevention of prostate cancer using inhibition of PGE2 receptors and HuR suppression by green tea polyphenol
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批准号:25462488
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.24万
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Elucidation of the unidentified molecular structure of the cell volume-sensitive anion channel
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批准号:24659095
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.5万
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依托单位:
Establishment of Theory Determining Self Assembling State of Amphiphilic Molecules Considering Steric Configuration and Steric Coordination
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批准号:23550217
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.41万
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财政年份:2011
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负责人:SAKAI Hideki
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依托单位:
Development of Pedagogical Reading Tasks for EFL on the Basis of Genre-Text-Types of Junior High School English Textbooks
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批准号:23520668
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.83万
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财政年份:2011
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依托单位:
Study on safety way guidance systems using phosphorescent materials
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批准号:22650171
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$1.37万
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负责人:SAKAI Hideki
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依托单位:
Clarification of properties of chloride channels, SLC26A7 and 26A9, involved in novel cytoprotective mechanism
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批准号:21390056
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.57万
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财政年份:2009
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负责人:SAKAI Hideki
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依托单位:
Validating L2 Writing Tasks on the Basis of Processability Theory
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批准号:21720194
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$1.08万
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财政年份:2009
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负责人:SAKAI Hideki
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依托单位:
The influence of attention to form in L2 listening comprehension
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批准号:19720133
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$0.95万
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依托单位:
Development of a directional high-reflective material for reducing the heat island effect
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.08万
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负责人:SAKAI Hideki
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依托单位:
Preparation of nano-structured photocatalyst using self-organized catalyst
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批准号:18550182
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.82万
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负责人:SAKAI Hideki
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依托单位:
Molecular Physiological Mechanism of Chloride Ion Secretion by CLC-5 and KCC4 associated with Gastric Proton Pump
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批准号:18390064
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$5.43万
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财政年份:2006
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负责人:SAKAI Hideki
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依托单位:
A study of gene-expression profile in knock-in mouse prostate cancer model
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批准号:17591685
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.11万
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负责人:SAKAI Hideki
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依托单位:
DNA microarray analysis in transgenic mouse prostate cancer model
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批准号:15390494
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.32万
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负责人:SAKAI Hideki
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依托单位:
Novel physiological function of CLC-5 chloride channel associated with gastric proton pump
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批准号:15390062
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$3.9万
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负责人:SAKAI Hideki
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依托单位:
Cytoprotective chloride channels as a molecular target for stress-related factors
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批准号:13670038
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项目类别:Grant-in-Aid for Scientific Research (C)
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依托单位:
Molecular and functional relations and intracellular polarized movement of the functional molecules in stomach and intestine.
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批准号:12144205
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$21.63万
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财政年份:2000
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负责人:SAKAI Hideki
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依托单位:
Significance of aberrant β-microseminoprotein expression in prostate cancer
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批准号:11671562
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Interphase cytogenetic analysis in adrenal neoplasms
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负责人:SAKAI Hideki
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依托单位:
海外基金