Functional interaction between chewing and swallowing center

咀嚼和吞咽中枢之间的功能相互作用

• 批准号: 20592170
• 负责人: INOUE Makoto
• 金额: $ 2.91万
• 依托单位: Niigata University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20592170/
• 关键词: 生理学; 脳・神経; 食品; 動物; ヒト; 反射

The aim of the study was (1) to clarify the neuronal interaction between peripheral and central mechanisms to complete mastication and (2) to evaluate the effects of food consistency on the movements using physiological methods. We found that jaw-opening reflex evoked by the trigeminal nerve was inhibited by the electrical stimulation of superior laryngeal nerve and suggested that this inhibition was due to the activation of swallowing center. We also successfully showed facilitation of voluntary swallowing by the electrical stimulation of mid- and hypophaynx in humans.

该研究的目的是（1）阐明完成咀嚼的外周和中枢机制之间的神经元相互作用；（2）使用生理方法评估食物稠度对运动的影响。我们发现三叉神经引起的张颌反射受到喉上神经电刺激的抑制，提示这种抑制是由于吞咽中枢的激活所致。我们还成功地证明了通过电刺激人类的中咽部和下咽部来促进自主吞咽。

项目成果

Brainstem neurons receiving inputs from the superior laryngeal nerve and their involvements in the swallowing.

脑干神经元接收来自喉上神经的输入并参与吞咽。

• 发表时间: 2010
• 作者: Inoue M;Tsujimura T;Fukuhara T;Kajii Y;Hayashi
• 通讯作者: Hayashi

Effects of afferent inputs from superior laryngeal nerve on the jaw opening reflex responses.

喉上神经传入输入对张颌反射反应的影响。

• 发表时间: 2010
• 作者: 福原孝子;辻村恭憲;梶井友佳;林宏和;井上誠
• 通讯作者: 井上誠

摂食行動に伴う開口反射の変調.

与进食行为相关的张口反射的调节。

• 发表时间: 2009
• 作者: 大久保厚司;三島弘幸;辻本恭久;松永常典;山本真也,福原孝子,梶井友佳,辻村恭憲,井上誠
• 通讯作者: 山本真也,福原孝子,梶井友佳,辻村恭憲,井上誠

咳嗽嚥下の臨床応用への可能性.

咳嗽吞咽临床应用的可能性。

• 发表时间: 2008
• 作者: 成清綾;吉田好紀;佐伯万騎男;井上美香;島田佳奈;江草宏;丹羽均;由良義明;矢谷博文;上崎善規;安達大雅,谷口裕重,梶井友佳,井上誠
• 通讯作者: 安達大雅,谷口裕重,梶井友佳,井上誠

Effects of electrical stimulation of the superior laryngeal nerve on the jaw-opening reflex in the rabbit.

电刺激喉上神经对家兔张颌反射的影响。

• 发表时间: 2010
• 作者: Makoto Inoue;Takanori Tsujimura;Takako Fukuhara
• 通讯作者: Takako Fukuhara