Neuronal control of swallowing center on the trigeminal activity

吞咽中枢对三叉神经活动的神经元控制

• 批准号: 23659982
• 负责人: INOUE Makoto
• 金额: $ 2.33万
• 依托单位: Niigata University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23659982/
• 关键词: 嚥下; 三叉神経; 単一ニューロン; 動物; 単一ニューロン記録

The aim of this study was to examine the neuronal control of swallowing center on thetrigeminal neuronal activity and to clarify coordination of orofacial muscles in animals. Unit discharges were recorded from digastric and mylohyoid motoneurons and the patterns of them during swallowing were different. Moreover, trigeminal neuronal activity during swallowing was evaluated by measurement of jaw opening reflex. Not only chewing but also swallowing strongly inhibited the jaw opening reflex responses, suggesting that these behaviors or central neuronal network for chewing and swallowing may regulate the excitability of trigeminal neurons.

这项研究的目的是检查吞咽神经元活性的吞咽中心的神经元控制，并阐明动物中口面肌肉的协调。记录了二胃和肌羟基运动神经元的单位放电，吞咽过程中的单位放电不同。此外，通过测量下颌打开反射来评估吞咽过程中三叉神经元活性。不仅咀嚼，而且吞咽也强烈抑制了颌骨的反射反应，这表明这些行为或中央神经元网络用于咀嚼和吞咽，可以调节三叉神经元的兴奋性。

项目成果

Effects of chewing and swallowing behavior on jaw opening reflex responses in naturally feeding rabbits

咀嚼和吞咽行为对自然喂养兔张颌反射反应的影响

• DOI: 10.1016/j.neulet.2012.12.047
• 发表时间: 2013
• 期刊: Neuroscience Letters
• 影响因子: 2.5
• 作者: Saitoh I;Sato M;Iwase Y;Akasaka E;Yamasaki Y;Noguchi H;Aki Yamada
• 通讯作者: Aki Yamada

Effects of the superior laryngeal nerve stimulation on the jaw-opening reflex in rabbits

喉上神经刺激对家兔张颌反射的影响

• 发表时间: 2011
• 作者: Takako Fukuhara;Takanori Tsujimura;Aki Yamada;Yuka Kajii;Makoto Inoue
• 通讯作者: Makoto Inoue

Organization of pERK-immunoreactive cells in trigeminal spinal nucleus caudalis, upper cervical cord, NTS and Pa5 following capsaicin injection into masticatory and swallowing-related muscles in rats

将辣椒素注射到大鼠咀嚼和吞咽相关肌肉后，三叉神经尾核、上颈髓、NTS 和 Pa5 中 pERK 免疫反应细胞的组织

• 发表时间: 2011
• 期刊: Brain Res
• 影响因子: 2.9
• 作者: Tsujimura T;Shinoda M;Honda K;Hitomi S;Kiyomoto M;Matsuura S;Katagiri A;Tsuji K;Inoue M;Shiga Y;Iwata K
• 通讯作者: Iwata K

The Digastric Muscle is Less Involved in Pharyngeal Swallowing in Rabbits

• DOI: 10.1007/s00455-011-9363-z
• 发表时间: 2012-06-01
• 期刊: DYSPHAGIA
• 影响因子: 2.6
• 作者: Tsujimura, Takanori;Yamada, Aki;Inoue, Makoto
• 通讯作者: Inoue, Makoto

自由行動下ウサギにおける開口反射の変調

自由活动兔子张口反射的调节

• 发表时间: 2012
• 作者: Tsujimura T;Shinoda M;Honda K;Hitomi S;Kiyomoto M;Matsuura S;Katagiri A;Tsuji K;Inoue M;Shiga Y;Iwata K;井上誠;山田亜紀,辻村恭憲,梶井友佳,福原孝子,井上誠
• 通讯作者: 山田亜紀,辻村恭憲,梶井友佳,福原孝子,井上誠