Regulation of cell survival and malignant tumor formation by Drs/GADD34
Regulation of cell survival and malignant tumor formation by Drs/GADD34
批准号:
21590437
负责人:
INOUE Hirokazu
金额:
$3.0万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
We investigated the role of Drs/GADD34 in cell responses under various stress conditions by using gene knockout cells and found that Drs plays critical roles for the control of cell responses in energy deprivation, hypoxia, energy metabolism and viral infection. Drs binds to GADD34 to regulate mTOR pathway via TSC1/2 phosphorylation control
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Role of cyclin D1b variant in rectal tumorigenesis
细胞周期蛋白 D1b 变异在直肠肿瘤发生中的作用
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Chul Jang Kim, Yukihiro Tambe, Takahiro Isono, Ken ichi Mukaisho, Hiroyuki Sugihara, Gen Kondoh, Hirokazu Inoue]
通讯作者:
Hirokazu Inoue
RBCC1 activates RB1 pathway and inhibits proliferation and cologenic survival in human cancer.
RBCC1 激活 RB1 通路并抑制人类癌症的增殖和结肠存活。
DOI:
--
发表时间:
2010
期刊:
PLos ONE
影响因子:
3.7
作者:
[Chano, T., Ikebuchi, K., Ochi, Y., Tameno, H., Tomita, Y., Jin, Y., Inaji, H., Ishitobi, M., Teramoto, K., Nishimura, I., Minami, K., Inoue, H., Isono, T., Saitoh, M., Shimada, T., Hisa, Y., Okabe, H.]
通讯作者:
H.
Cell-type dependent regulation of EMT and cell invasiveness of cancer cells by periostin
骨膜素对 EMT 和癌细胞侵袭性的细胞类型依赖性调节
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Chul Jang Kim, Yukihiro Tambe, Hirokazu Inoue]
通讯作者:
Hirokazu Inoue
DOI:
10.3892/ijo.2011.997
发表时间:
2011-06-01
期刊:
INTERNATIONAL JOURNAL OF ONCOLOGY
影响因子:
5.2
作者:
[Kim, Chul Jang, Sakamoto, Kanami, Inoue, Hirokazu]
通讯作者:
Inoue, Hirokazu
RBCC1 together with RB1 and p53predicts long-term survival in Japanese breast cancer patients
RBCC1 与 RB1 和 p53 一起预测日本乳腺癌患者的长期生存
DOI:
--
发表时间:
2010
期刊:
PLos ONE
影响因子:
3.7
作者:
[Chano T, Ikebuchi K, Tomita Y, Jin Y, Inaji H, Ishitobi M, Teramoto K, Ochi Y, Tameno H, Nishimura I, Minami K, Inoue H, Isono T, Saitoh M, Shimada T, Hisa Y. Okabe H]
通讯作者:
Hisa Y. Okabe H
共 22 条
Studies of novel mechanism of colorectal carcinogenesis by cyclin D1b-transgenic mouse
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批准号:24590480
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.41万
-
财政年份:2012
-
负责人:INOUE Hirokazu
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依托单位:
Mechanism of mtDNA deletion in short lived mutant of Neurospora.
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批准号:20570001
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.08万
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财政年份:2008
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负责人:INOUE Hirokazu
-
依托单位:
Regulation of apoptosis and autophagy under stress conditions and cancer progression
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批准号:19590388
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
-
财政年份:2007
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负责人:INOUE Hirokazu
-
依托单位:
Host for highly efficient gene targeting in filamentous fungi
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批准号:18370001
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$6.03万
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财政年份:2006
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负责人:INOUE Hirokazu
-
依托单位:
Studies on the mechanism of Drs-mediated apoptosis and tumor suppression by gene-knockout mouse
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批准号:17590341
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
-
财政年份:2005
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负责人:INOUE Hirokazu
-
依托单位:
Functional analyses of novel tumor suppressor genes by gene targeting
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批准号:15590335
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
-
财政年份:2003
-
负责人:INOUE Hirokazu
-
依托单位:
Studies on molecular mechanism of tumor suppression by the drs gene
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批准号:13670211
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
-
财政年份:2001
-
负责人:INOUE Hirokazu
-
依托单位:
Characterization of the mus-10 and recQ genes involving in DNA repair, recombination, and senescence
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批准号:11640619
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:1999
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负责人:INOUE Hirokazu
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依托单位:
Isolation and functional analysis of the genes involved in suppression of transformation in primary cells
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批准号:10670205
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.98万
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财政年份:1998
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负责人:INOUE Hirokazu
-
依托单位:
Studies on suppression of transformation in primary rat embryo fibroblasts
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批准号:07670244
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.47万
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财政年份:1995
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负责人:INOUE Hirokazu
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依托单位:
Cloning and Analysis of Neurospora genes which work on homologous recombination
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批准号:06640794
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1994
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负责人:INOUE Hirokazu
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依托单位:
Effects of DNA repair on homologous and non-homologous recombination
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批准号:04640592
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.09万
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财政年份:1992
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负责人:INOUE Hirokazu
-
依托单位:
海外基金