A crossover study of a traditional Asian medicine for Huntington's disease

亚洲传统药物治疗亨廷顿病的交叉研究

• 批准号: 21591107
• 负责人: IWASAKI Koh
• 金额: $ 2.83万
• 依托单位: 独立行政法人国立病院機構西多賀病院 (2011)Tohoku University (2009-2010)
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21591107/
• 关键词: 臨床神経治療学; ハンチントン病; 抑肝散; 漢方; 東洋医学; 不随意運動; ジストニア; 舞踏症状

A two-way crossover study of a traditional Asian herbal medicine yokukansan(YKS) was conducted for Huntington's disease(HD). YKS showed a tendency for improvement of Total Unified Huntington's Disease Rating Scale, Maximal Chorea, and Maximal Dystonia.

对传统亚洲草药横叶参（YKS）治疗亨廷顿舞蹈病（HD）进行了双向交叉研究。全统一亨廷顿病评定量表、最大舞蹈病、最大肌张力障碍均有改善的趋势。

项目成果

Yokukansan, a traditional Japanese medicine, ameliorates memory disturbance and abnormal social interaction with anti-aggregation effect of cerebral amyloidβproteins in amylod precursor protein transgenic mice

日本传统药物抑肝散通过抗淀粉样蛋白前体蛋白转基因小鼠脑淀粉样蛋白聚集作用改善记忆障碍和异常社交互动

• 发表时间: 2011
• 期刊: Neuroscience
• 影响因子: 3.3
• 作者: Fujiwara H;Takayama S;Iwasaki K;Tabuchi M;Yamaguchi T;Sekiguchi K;Ikarashi Y;Kudo Y;Kase Y;Arai H;and Yaegashi N
• 通讯作者: and Yaegashi N

YOKUKANSAN, A TRADITIONAL JAPANESE MEDICINE, AMELIORATES MEMORY DISTURBANCE AND ABNORMAL SOCIAL INTERACTION WITH ANTI-AGGREGATION EFFECT OF CEREBRAL AMYLOID β PROTEINS IN AMYLOID PRECURSOR PROTEIN TRANSGENIC MICE

• DOI: 10.1016/j.neuroscience.2011.01.064
• 发表时间: 2011-04-28
• 期刊: NEUROSCIENCE
• 影响因子: 3.3
• 作者: Fujiwara, H.;Takayama, S.;Yaegashi, N.
• 通讯作者: Yaegashi, N.

A crossover study of a traditional Asian herbal medicine for Hutington's diseasePoster presentation

传统亚洲草药治疗赫廷顿病的交叉研究海报展示

• 发表时间: 2011
• 作者: Iwasaki K;et at
• 通讯作者: et at

Efficacy and safety of yokukansan, a traditional Asian medicine, for BPSD in Dementia with Lewy Bodies

传统亚洲药物抑肝散治疗路易体痴呆症 BPSD 的功效和安全性

• 发表时间: 2010
• 作者: Iwasaki K;et at
• 通讯作者: et at

A crossover study of a traditional Asian herbal medicine for Huntington's disease

亚洲传统草药治疗亨廷顿病的交叉研究

• 发表时间: 2011
• 作者: K.Iwasaki;A.Kikuchi
• 通讯作者: A.Kikuchi